中国现代医生
中國現代醫生
중국현대의생
CHINA MODERN DOCTOR
2015年
11期
69-71
,共3页
李雯霖%何爱群%卓晓%林海波%陈慕丹
李雯霖%何愛群%卓曉%林海波%陳慕丹
리문림%하애군%탁효%림해파%진모단
TGF-β1%IL-17%过敏性结膜炎
TGF-β1%IL-17%過敏性結膜炎
TGF-β1%IL-17%과민성결막염
TGF-β1%IL-17%Allergic conjunctivitis
目的:探讨过敏性结膜炎患者TGF-β1和IL-17的表达水平。方法对我院治疗的过敏性结膜炎患者和健康人群的TGF-β1和IL-17的表达水平进行检测,探讨在各型过敏性结膜炎患者中的表达强度。结果过敏性结膜炎患者TGF-β1和IL-17水平高于健康人群,差异有统计学意义(P<0.01),过敏性结膜炎四个临床亚型中TGF-β1和IL-17的表达水平不一,以春季角结膜炎表达水平最高,其次为常年性过敏性结膜炎和季节性过敏性结膜炎,特应性角结膜炎表达水平最低,但四个临床亚型组间比较差异无统计学意义(P>0.05)。结论过敏性结膜炎患者TGF-β1和IL-17表达水平高于正常健康人群。 TGF-β1和陨蕴-17在各型过敏性结膜炎患者中表达强度不同,在春季角结膜炎表达水平明显高于其他类型。
目的:探討過敏性結膜炎患者TGF-β1和IL-17的錶達水平。方法對我院治療的過敏性結膜炎患者和健康人群的TGF-β1和IL-17的錶達水平進行檢測,探討在各型過敏性結膜炎患者中的錶達彊度。結果過敏性結膜炎患者TGF-β1和IL-17水平高于健康人群,差異有統計學意義(P<0.01),過敏性結膜炎四箇臨床亞型中TGF-β1和IL-17的錶達水平不一,以春季角結膜炎錶達水平最高,其次為常年性過敏性結膜炎和季節性過敏性結膜炎,特應性角結膜炎錶達水平最低,但四箇臨床亞型組間比較差異無統計學意義(P>0.05)。結論過敏性結膜炎患者TGF-β1和IL-17錶達水平高于正常健康人群。 TGF-β1和隕蘊-17在各型過敏性結膜炎患者中錶達彊度不同,在春季角結膜炎錶達水平明顯高于其他類型。
목적:탐토과민성결막염환자TGF-β1화IL-17적표체수평。방법대아원치료적과민성결막염환자화건강인군적TGF-β1화IL-17적표체수평진행검측,탐토재각형과민성결막염환자중적표체강도。결과과민성결막염환자TGF-β1화IL-17수평고우건강인군,차이유통계학의의(P<0.01),과민성결막염사개림상아형중TGF-β1화IL-17적표체수평불일,이춘계각결막염표체수평최고,기차위상년성과민성결막염화계절성과민성결막염,특응성각결막염표체수평최저,단사개림상아형조간비교차이무통계학의의(P>0.05)。결론과민성결막염환자TGF-β1화IL-17표체수평고우정상건강인군。 TGF-β1화운온-17재각형과민성결막염환자중표체강도불동,재춘계각결막염표체수평명현고우기타류형。
Objective To investigate the expression level of transforming growth factorβ1 (TGF-β1) and interleukin 17 (IL-17) in patients with allergic conjunctivitis. Methods TGF-β1 and IL-17 expression levels in allergic conjunctivitis patients hospitalized in the author's hospital and a healthy population were detected to explore the expression level in all types of patients with allergic conjunctivitis. Results TGF-β1 and IL-17 levels were significantly higher in patients with allergic conjunctivitis than in healthy population (P<0.01). Among the four clinical subtypes of allergic conjunctivi-tis, vernal keratoconjunctivitis had the highest expression level of TGF-β1 and IL-17 in spring, followed by perennial allergic conjunctivitis and seasonal allergic conjunctivitis, and atopic keratoconjunctivitis had the lowest expression level. However, the differences among the four subtypes were not significant (P>0.05). Conclusion Patients with allergic conjunctivitis have higher TGF-β1 and IL-17 expression levels than normal healthy people. TGF-β1 and IL-17 ex-pression level vary in different subtypes of allergic conjunctivitis, vernal keratoconjunctivitis has higher expression level than other types in spring.