CAJ | 학술논문

目的：观察在常规治疗基础上加用口服孟鲁司特治疗支气管扩张症的临床疗效。方法选取2010年4月至2012年4月医院住院诊治患者77例，按照随机数字表法分成治疗组39例和对照组38例。对照组给予常规治疗，治疗组在此基础上加用孟鲁司特口服，每次10 mg，1日1次。观察两组患者治疗前后痰量、影像学改变及肺功能等并进行比较。结果治疗组总有效率为92.31%，显著高于对照组的73.68%（ P ﹤0.05）；治疗组肺功能指标与对照组比较，有明显改善（ P ﹤0.05）。结论在常规治疗的基础上加服孟鲁司特治疗支气管扩张症，可明显提高临床疗效，改善患者生活质量，值得临床推广。
목적：관찰재상규치료기출상가용구복맹로사특치료지기관확장증적림상료효。방법선취2010년4월지2012년4월의원주원진치환자77례，안조수궤수자표법분성치료조39례화대조조38례。대조조급여상규치료，치료조재차기출상가용맹로사특구복，매차10 mg，1일1차。관찰량조환자치료전후담량、영상학개변급폐공능등병진행비교。결과치료조총유효솔위92.31%，현저고우대조조적73.68%（ P ﹤0.05）；치료조폐공능지표여대조조비교，유명현개선（ P ﹤0.05）。결론재상규치료적기출상가복맹로사특치료지기관확장증，가명현제고림상료효，개선환자생활질량，치득림상추엄。
Objective To observe the clinical efficacy of adding oral montelukast on the basis of the conventional therapy in treating bronchiectasis. Methods 77 inpatients with bronchiectasis in our hospital from April 2010 to April 2012 were selected and randomly divided into the treatment group(39 cases) and the control group(38 cases) according to the random number method. The control group was given the conventional treatment, while on this basis the treatment group was added with oral montelukast 10 mg, once daily. The sputum volume, imaging changes, lung function, and other clinically relevant efficacy parameters before and after treatment were recorded and compared between the two groups. Results The effective rate was 92. 31% in the treatment group and 73. 68% in the control group, the treatment group was significantly higher than the control group with statistically significant difference ( P ﹤ 0. 05) . The lung function of the treatment group was significantly improved compared with the control group ( P ﹤ 0. 05) . Conclusion Adding oral ad-ministration of montelukast on the basis of the conventional therapy for treating bronchiectasis can obviously increase the curative effica-cy, improve the life quality of patients and deserves to be clinically promoted.