CAJ | 학술논문

1例57岁乳腺癌女性患者接受表柔比星(第1、2天各50 mg静脉滴注)和多西他赛(第1天100 mg静脉滴注)联合化疗.化疗前骨髓象正常.第1个化疗周期第11天患者出现发热、乏力、水样便等症状,血常规检查示外周血白细胞计数(WBC) 1.7×109/L,红细胞计数(RBC) 3.2×1012/L,血红蛋白(Hb) 101 g/L,血小板计数(PLT) 65×109/L;第13天,WBC 0.08×109/L,中性粒细胞计数(NEUT) 0,RBC 3.3×1012/L,Hb 101 g/L,PLT 31×109/L;第14天WBC 0.1×109/L,NEUT 0,RBC2.6×1012/L,Hb 89 g/L,PLT 7×109/L.患者继发重症肺炎和急性呼吸窘迫综合征.虽积极给予抗感染、升白细胞等对症支持治疗,但患者病情无明显好转,终因呼吸、循环衰竭于化疗周期第14天死亡.
1례57세유선암녀성환자접수표유비성(제1、2천각50 mg정맥적주)화다서타새(제1천100 mg정맥적주)연합화료.화료전골수상정상.제1개화료주기제11천환자출현발열、핍력、수양편등증상,혈상규검사시외주혈백세포계수(WBC) 1.7×109/L,홍세포계수(RBC) 3.2×1012/L,혈홍단백(Hb) 101 g/L,혈소판계수(PLT) 65×109/L;제13천,WBC 0.08×109/L,중성립세포계수(NEUT) 0,RBC 3.3×1012/L,Hb 101 g/L,PLT 31×109/L;제14천WBC 0.1×109/L,NEUT 0,RBC2.6×1012/L,Hb 89 g/L,PLT 7×109/L.환자계발중증폐염화급성호흡군박종합정.수적겁급여항감염、승백세포등대증지지치료,단환자병정무명현호전,종인호흡、순배쇠갈우화료주기제14천사망.
A 57-year-old woman with breast cancer received combined chemotherapy of epirubicin (an Ⅳ infusion of 50 mg on day 1 and day 2) and docetaxel (an Ⅳ infusion of 100 mg on day 1).Her myelogram was normal before chemotherapy.On day 11 of the first period of chemotherapy,she developed fever,hypodynamia,and watery stool.The blood routine examination showed white blood cell count (WBC) 1.7 × 109/L,red blood cell count (RBC) 3.2 × 1012/L,hemoglobin (Hb) 101 g/L,platelet count (PLT) 65 × 109/L.On day 13,the examination showed WBC 0.08 × 109/L,neutrophil count (NEUT) 0,RBC 3.3 × 1012/L,Hb 101 g/L,PLT31 × 109/L.On day 14,WBC 0.1 × 109/L,NEUT 0,RBC 2.6 × 1012/L,Hb 89 g/L,PLT 7 × 109/L.The patient developed secondary severe pneumonia and acute respiratory distress syndrome.The symptomatic and supportive treatments including anti-infection and stimulating leukocytes production were given.However,the patient's condition did not improve significantly.On day 14 of the first period of chemotherapy,the patient eventually died due to respiratory and circulatory failure.