CAJ | 학술논문

目的：评价中西药联合治疗反流性咽喉炎的疗效。方法126例慢性咽炎患者随机分为对照组60例和观察组66例，对照组口服多潘立酮10 mg，1日3次，口服奥美拉唑20 mg，1日2次，均为饭后服用。在与对照组相同服药的基础上，观察组另外口服中药威灵仙方剂，分2次温服，每日1剂，疗程4周。观察2组的疗效与药物不良反应。结果观察组总有效率87.9％，明显高于对照组的68.3％（ P＜0.05）。2组均未发生药物不良反应。结论中西结合对于反流性咽喉炎有着很好的临床治疗效果且安全性较好。
목적：평개중서약연합치료반류성인후염적료효。방법126례만성인염환자수궤분위대조조60례화관찰조66례，대조조구복다반립동10 mg，1일3차，구복오미랍서20 mg，1일2차，균위반후복용。재여대조조상동복약적기출상，관찰조령외구복중약위령선방제，분2차온복，매일1제，료정4주。관찰2조적료효여약물불량반응。결과관찰조총유효솔87.9％，명현고우대조조적68.3％（ P＜0.05）。2조균미발생약물불량반응。결론중서결합대우반류성인후염유착흔호적림상치료효과차안전성교호。
Objective To evaluate the effect of combined therapy of traditional Chinese and western medicine on laryngopharyngeal reflux disease .Methods One hundred and twenty -six patients with laryngo-pharyngeal reflux disease were divided into two groups:control group and observe group, including 60 and 66 patients, respectively.The patients in two groups were given basic treatment .The patients in control group were given basic treatment , domperidone ( 10 mg · d-1 , three times a day) and omeprazole (20 mg· d-1, twice a day).Both drugs were taken after meal .The patients in observe group were given Weilingxian except basic treatment , a traditional Chinese medicine .Four weeks later after administration , curative effects were compared .The adverse drug reaction after treatment in two groups were investigated .Results The total efficacy rate of observe group was 87.9%, higher than the control group, which was 68.3%, the difference was statistically significant (P<0.05).There were no adverse drug reaction occurrence in two groups.Conclusion Combined therapy of traditional Chinese and western medicine on laryngopharyngeal reflux disease have better clinical effects.