CAJ | 학술논문

伪膜性肠炎的发生与抗生素的使用密切相关,其致病菌约100％为艰难梭菌.诊断主要是在临床表现的基础上通过粪便培养、毒素检测、结肠镜检查和(或)组织学检查.一旦确诊或高度怀疑本病,应立即停用原有抗生素,以甲硝唑和(或)万古霉素抗感染治疗,并辅以益生菌及营养支持治疗.近年来,仍出现新型的治疗方案.该文对伪膜性肠炎的相关情况进行阐述,以提高临床医生对其的认识.
위막성장염적발생여항생소적사용밀절상관,기치병균약100％위간난사균.진단주요시재림상표현적기출상통과분편배양、독소검측、결장경검사화(혹)조직학검사.일단학진혹고도부의본병,응립즉정용원유항생소,이갑초서화(혹)만고매소항감염치료,병보이익생균급영양지지치료.근년래,잉출현신형적치료방안.해문대위막성장염적상관정황진행천술,이제고림상의생대기적인식.
Pseudomembranous colitis occurred is closely related to the use of antibiotics and the pathogenic bacteria approximately 100％ is clostridium difficile.Diagnosis is mainly based on clinical manifestations,stool culture,toxin detection,colonoscopy and/or histological examination.Once the diagnosis has been confirmed or highly suspected,the initial antibiotic therapy should be discontinued,add with metronidazole and/or vancomycin,supplement by probiotic and nutritional support.The recent years,new treatment options have been proposed.This article presents an review of the related situation of pseudomembranous colitis to improve the comprehension for clinical doctors.