齐齐哈尔医学院学报
齊齊哈爾醫學院學報
제제합이의학원학보
JOURNAL OF QIQIHAR MEDICAL COLLEGE
2015年
9期
1292-1293
,共2页
液基薄层细胞学%人乳头瘤病毒%宫颈疾病%临床意义
液基薄層細胞學%人乳頭瘤病毒%宮頸疾病%臨床意義
액기박층세포학%인유두류병독%궁경질병%림상의의
Liquid thin-layer cytology%Human papillomavirus ( HPV)%The cervical disease%Clinical significance
目的：研究薄层液基细胞学检查（ TCT）联合高危型人乳头瘤病毒（ HPV）在宫颈病变筛查中的临床意义。方法通过回顾性分析2013年1月至2014年6月在肇庆市端州区妇幼保健院接受宫颈疾病筛查的妇女500例，同时行TCT、HPV基因分型检测对阳性病例均行阴道镜检查并取活检，对TCT组、HPV组、TCT＋HPV组阳性病例与病理结果诊断的符合率进行分析和比较。结果500例筛查人群中，TCT阳性的有94例，占18．8％，在阴道镜指导下取活检，病例组织学阳性例数58例，阳性符合率61．7％；高危性HPV阳性的有117例，占23．4％，病例组织学阳性例数71例，阳性符合率60．68％；TCT联合高危型HPV 同时阳性的有63例，占12．6％，病例组织学阳性例数49例，阳性符合率77．78％。结论 TCT联合HPV与病理检查的阳性符合率明显高于其中单项检查与病理检查的阳性符合率，其更有效的早期发现宫颈癌前病变和宫颈癌，在临床上具有重要的意义。
目的：研究薄層液基細胞學檢查（ TCT）聯閤高危型人乳頭瘤病毒（ HPV）在宮頸病變篩查中的臨床意義。方法通過迴顧性分析2013年1月至2014年6月在肇慶市耑州區婦幼保健院接受宮頸疾病篩查的婦女500例，同時行TCT、HPV基因分型檢測對暘性病例均行陰道鏡檢查併取活檢，對TCT組、HPV組、TCT＋HPV組暘性病例與病理結果診斷的符閤率進行分析和比較。結果500例篩查人群中，TCT暘性的有94例，佔18．8％，在陰道鏡指導下取活檢，病例組織學暘性例數58例，暘性符閤率61．7％；高危性HPV暘性的有117例，佔23．4％，病例組織學暘性例數71例，暘性符閤率60．68％；TCT聯閤高危型HPV 同時暘性的有63例，佔12．6％，病例組織學暘性例數49例，暘性符閤率77．78％。結論 TCT聯閤HPV與病理檢查的暘性符閤率明顯高于其中單項檢查與病理檢查的暘性符閤率，其更有效的早期髮現宮頸癌前病變和宮頸癌，在臨床上具有重要的意義。
목적：연구박층액기세포학검사（ TCT）연합고위형인유두류병독（ HPV）재궁경병변사사중적림상의의。방법통과회고성분석2013년1월지2014년6월재조경시단주구부유보건원접수궁경질병사사적부녀500례，동시행TCT、HPV기인분형검측대양성병례균행음도경검사병취활검，대TCT조、HPV조、TCT＋HPV조양성병례여병리결과진단적부합솔진행분석화비교。결과500례사사인군중，TCT양성적유94례，점18．8％，재음도경지도하취활검，병례조직학양성례수58례，양성부합솔61．7％；고위성HPV양성적유117례，점23．4％，병례조직학양성례수71례，양성부합솔60．68％；TCT연합고위형HPV 동시양성적유63례，점12．6％，병례조직학양성례수49례，양성부합솔77．78％。결론 TCT연합HPV여병리검사적양성부합솔명현고우기중단항검사여병리검사적양성부합솔，기경유효적조기발현궁경암전병변화궁경암，재림상상구유중요적의의。
Objective The thin layer of liquid based cytology ( TCT) joint type of high-rwask human papilloma virus ( HPV) in clinical significance in screening of cervical lesions.Methods By retrospective analysis in January 2013 to June 2013 in Zhaoqing Duanzhou district maternity and child care to accept the women and 500 cases of cervical disease screening and TCT, detect HPV genotyping of positive cases all colposcope examination and biopsy, the TCT, HPV, TCT +HPV positive cases and the accuracy of pathological diagnosis results were analyzed and compared.Results 500 cases of screening the crowd, TCT positive in 94 patients, 18.8%, take a biopsy under colposcope, histologic positive cases 58 cases, positive coincidence rate 61.7%;High-risk sexual HPV positive with 117 cases, accounting for 23.4%, case histologic positive cases 71 cases positive coincidence rate 60.68%; TCT joint high-risk type HPV positive in 63 patients at the same time, accounting for 12.6%, case histologic positive cases in 49 cases, positive coincidence rate was 77.78%. Conclusions TCT joint HPV and positive coincidence rate of pathologic examination is obviously higher than that of the individual examination and pathological examination of positive coincidence rate, the more effective before the early detection of cervical lesions and cervical cancer, has the vital significance in clinic.
