CAJ | 학술논문

目的：探讨喘可治注射液雾化吸入治疗慢性阻塞性肺疾病急性发作的临床疗效。方法选取2013年7月至2014年7月我院收治的116例慢性阻塞性肺疾病急性发作患者作为研究对象，采用随机数字表法将所选患者分为研究组和对照组，各58例，对照组给予西医常规治疗联合甲强龙治疗，研究组在常规治疗基础上给予喘可治注射液雾化吸入治疗。综合比较两组患者治疗总有效率、治疗前后肺功能情况及不良反应发生情况。结果研究组治疗总有效率为89．66％，高于对照组的81．03％，组间比较差异无统计学意义（P＞0．05）；治疗7 d后，研究组FEV1／FVC和FEV1％均优于对照组（P＜0．05）；研究组不良反应发生率低于对照组（P＜0．01）。结论喘可治注射液雾化吸入治疗慢性阻塞性肺疾病急性发作效果确切，可明显改善临床症状，改善肺功能，值得临床推广使用。
목적：탐토천가치주사액무화흡입치료만성조새성폐질병급성발작적림상료효。방법선취2013년7월지2014년7월아원수치적116례만성조새성폐질병급성발작환자작위연구대상，채용수궤수자표법장소선환자분위연구조화대조조，각58례，대조조급여서의상규치료연합갑강룡치료，연구조재상규치료기출상급여천가치주사액무화흡입치료。종합비교량조환자치료총유효솔、치료전후폐공능정황급불량반응발생정황。결과연구조치료총유효솔위89．66％，고우대조조적81．03％，조간비교차이무통계학의의（P＞0．05）；치료7 d후，연구조FEV1／FVC화FEV1％균우우대조조（P＜0．05）；연구조불량반응발생솔저우대조조（P＜0．01）。결론천가치주사액무화흡입치료만성조새성폐질병급성발작효과학절，가명현개선림상증상，개선폐공능，치득림상추엄사용。
Objective This paper was to investigate the effects of Chuankezhiatomizing inhalation in the treatment of chronic obstructive pulmonary diseaseacute exacerbation.Methods 116 cases of patients with acute exacerbation of chronic obstructive pulmonary disease in our hospital were randomly divided into research group and control group,58 cases in each group.Patients in control group were treated with routine western medicine combined with methylprednisolone while patients in research group were treated with Chuankezhi inhalation.The total effective rate, lung function before and after the treatment and adverse events of the two groups were compared.Results The total effective rate of research group was 89.66%,which was higher than 81.03% of control group (P>0.05).7 days after treatment,FEV1/FVC and FEV1% of research group were better than control group (P<0.05).The adverse reactions rate of research group was lower than control group (P<0.05). Conclusions Chuankezhiatomizing inhalation can obtain exact effect in the treatment of chronic obstructive pulmonary diseaseacute exacerbation.It can effectively improve clinical symptoms and lung function.It is worthy of widelyclinical use.