CAJ | 학술논문

目的：回顾分析研究三联序贯疗法、单纯钻孔减压、单纯介入、单纯口服药物、减压+介入、减压+口服药物治的疗312髋成人早中期股骨头缺血性坏死患者。方法182例312髋均为Ficat Ⅰ～Ⅲ期患者，分别应用三联序贯疗法、单纯钻孔减压、单纯介入、单纯口服药物、减压+介入、减压+口服药物治疗，所有病例在治疗前，治疗后0.5年，治疗后1年，治疗后1.5年，治疗后2年进行Harris评分。结果治疗后0.5年，Ⅰ期内6组计量资料比较，无统计学意义（P>0.05）；Ⅱ期、Ⅲ期6组内三联疗法组优于其他治疗组，有统计学意义（P<0.05）；治疗后1年，Ⅰ期组内6组计量资料比较，无统计学意义（P>0.05），Ⅱ期、Ⅲ期6组内三联疗法组优于其它治疗组，有统计学意义（P<0.05）；治疗后1.5年，Ⅰ期、Ⅱ期、Ⅲ期6组内三联疗法组优于其它治疗组，有统计学意义（P<0.05）。治疗后2年，Ⅰ期、Ⅱ期、Ⅲ期6组内三联疗法组优于其它治疗组，有统计学意义（ P<0.05）。结论三联疗法对早中期成人股骨头缺血坏死的疗效显著高于单一治疗，是临床治疗早中期成人股骨头缺血性坏死的有效方法。
목적：회고분석연구삼련서관요법、단순찬공감압、단순개입、단순구복약물、감압+개입、감압+구복약물치적료312관성인조중기고골두결혈성배사환자。방법182례312관균위Ficat Ⅰ～Ⅲ기환자，분별응용삼련서관요법、단순찬공감압、단순개입、단순구복약물、감압+개입、감압+구복약물치료，소유병례재치료전，치료후0.5년，치료후1년，치료후1.5년，치료후2년진행Harris평분。결과치료후0.5년，Ⅰ기내6조계량자료비교，무통계학의의（P>0.05）；Ⅱ기、Ⅲ기6조내삼련요법조우우기타치료조，유통계학의의（P<0.05）；치료후1년，Ⅰ기조내6조계량자료비교，무통계학의의（P>0.05），Ⅱ기、Ⅲ기6조내삼련요법조우우기타치료조，유통계학의의（P<0.05）；치료후1.5년，Ⅰ기、Ⅱ기、Ⅲ기6조내삼련요법조우우기타치료조，유통계학의의（P<0.05）。치료후2년，Ⅰ기、Ⅱ기、Ⅲ기6조내삼련요법조우우기타치료조，유통계학의의（ P<0.05）。결론삼련요법대조중기성인고골두결혈배사적료효현저고우단일치료，시림상치료조중기성인고골두결혈성배사적유효방법。
Objective:To retrospectively analyze and research the applications of triple sequential therapy,simple drill-ing decompression,simple intervention,simple oral drugs,decompression and intervention,decompression and oral medi-cation to treat 312 hip of adult patients with early-to-middle femoral head avascular necrosis. Methods:182 patients with 312 hips were all in Ficat Ⅰ-Ⅲ stage,and received the applications of triple sequential therapy,simple drilling decom-pression,simple intervention,simple oral drugs,decompression and intervention,decompression and oral medication re-spectively,the Harris scoring was carried out among all cases before treatment,0. 5 year after treatment,1 year after treat-ment,1. 5 years after treatment and 2 years after treatment. Results:In 0. 5 year after treatmen,the 6 groups were com-pared,and measuring data of stageⅠhad no statistical significance(P>0. 05);triple sequential therapy were better than the other treatment methods among 6 groups,and measuring data between the stages Ⅱand Ⅲ had statistical significance (P<0. 05);1 year after treatment,6 groups were compared and measuring data of stageⅠhad no statistical significance (P>0. 05);triple sequential therapy were better than the other treatment methods among 6 groups and measuring data of stageⅡ,stage Ⅲ had statistical significance(P<0. 05);1. 5 years after the treatment,triple sequential therapy were better than the other treatment methods among 6 groups measuring data of stageⅠ,Ⅱ,Ⅲhad statistical significance( P<0. 05);2 years after the treatment,triple sequential therapy were better than the other treatment methods among 6 groups measuring data of stageⅠ,Ⅱ,Ⅲhad statistical significance(P<0. 05). Conclusion:The curative effect of triple sequen-tial therapy for adult with early-to-middle femoral head avascular necrosis is significantly higher than the single treat-ment,and triple sequential therapy is an effective clinical treatment for adults with early-to-middle femoral head avascular necrosis.