心脑血管病防治
心腦血管病防治
심뇌혈관병방치
PREVENTION AND TREATMENT OF CARDIO-CEREBRAL-VASCULAR DISEASE
2015年
2期
98-100
,共3页
慢性阻塞性肺疾病%肺动脉高压%肺功能%计算机体层摄影术
慢性阻塞性肺疾病%肺動脈高壓%肺功能%計算機體層攝影術
만성조새성폐질병%폐동맥고압%폐공능%계산궤체층섭영술
Chronic obstructive pulmonary disease%Pulmonary hypertension%Pulmonary function test%Computed tomography
目的：分析慢性阻塞性肺疾病（COPD ）并发肺动脉高压患者的临床特征，探讨胸部CT及肺功能对肺动脉高压的诊断价值。方法回顾性分析COPD患者72例，经超声心动图测量肺动脉收缩压（PASP ），根据PASP结果分为对照组、轻度肺动脉高压组、中重度肺动脉高压组，比较三组患者红细胞压积、血红蛋白、D_II聚体、动脉血气分析、肺功能、CT图像上的主肺动脉直径与主动脉直径等测值。结果中重度肺动脉高压组PaCO2显著高于对照组及轻度肺动脉高压组，差异有统计学意义（ P＜0.05）。相比对照组，轻度及中重度肺动脉高压组的主肺动脉直径、主肺动脉直径／降主动脉直径比值均大于对照组，差异有统计学意义（ P＜0.01），用力肺活量（FVC ）、一秒用力呼气容积（FEV1）、FEV1／FVC、一氧化碳弥散量差异均无统计学意义（ P＞0.05）。结论 CT中的主肺动脉直径及主肺动脉与降主动脉直径比值可作为筛查肺动脉高压的指标。
目的：分析慢性阻塞性肺疾病（COPD ）併髮肺動脈高壓患者的臨床特徵，探討胸部CT及肺功能對肺動脈高壓的診斷價值。方法迴顧性分析COPD患者72例，經超聲心動圖測量肺動脈收縮壓（PASP ），根據PASP結果分為對照組、輕度肺動脈高壓組、中重度肺動脈高壓組，比較三組患者紅細胞壓積、血紅蛋白、D_II聚體、動脈血氣分析、肺功能、CT圖像上的主肺動脈直徑與主動脈直徑等測值。結果中重度肺動脈高壓組PaCO2顯著高于對照組及輕度肺動脈高壓組，差異有統計學意義（ P＜0.05）。相比對照組，輕度及中重度肺動脈高壓組的主肺動脈直徑、主肺動脈直徑／降主動脈直徑比值均大于對照組，差異有統計學意義（ P＜0.01），用力肺活量（FVC ）、一秒用力呼氣容積（FEV1）、FEV1／FVC、一氧化碳瀰散量差異均無統計學意義（ P＞0.05）。結論 CT中的主肺動脈直徑及主肺動脈與降主動脈直徑比值可作為篩查肺動脈高壓的指標。
목적：분석만성조새성폐질병（COPD ）병발폐동맥고압환자적림상특정，탐토흉부CT급폐공능대폐동맥고압적진단개치。방법회고성분석COPD환자72례，경초성심동도측량폐동맥수축압（PASP ），근거PASP결과분위대조조、경도폐동맥고압조、중중도폐동맥고압조，비교삼조환자홍세포압적、혈홍단백、D_II취체、동맥혈기분석、폐공능、CT도상상적주폐동맥직경여주동맥직경등측치。결과중중도폐동맥고압조PaCO2현저고우대조조급경도폐동맥고압조，차이유통계학의의（ P＜0.05）。상비대조조，경도급중중도폐동맥고압조적주폐동맥직경、주폐동맥직경／강주동맥직경비치균대우대조조，차이유통계학의의（ P＜0.01），용력폐활량（FVC ）、일초용력호기용적（FEV1）、FEV1／FVC、일양화탄미산량차이균무통계학의의（ P＞0.05）。결론 CT중적주폐동맥직경급주폐동맥여강주동맥직경비치가작위사사폐동맥고압적지표。
Objective To investigate the clinical characteristics of patients with chronic obstructive pulmonary disease (COPD) associ-ated with pulmonary hypertension(PH) ,and evaluate the diagnostic value of pulmonary function test and chest computed tomography for predicting pulmonary hypertension.Methods Retrospective study of 72 patients with COPD ,all patients were divided into three groups according to pulmonary artery systolic pressure (PASP) measured by echocardiography. Hematokrit ,hemoglobin ,D_Dimer , blood_gas analysis ,pulmonary function test ,diameters of main pulmonary artery (MPAD) and aorta were compared among the groups.Results The PaCO2 in moderate_severe PH group was significantly higher than that of control group and mild PH group ,there were statistically significant differences ( P<0.05 ) .Compared with control group ,the MPAD and the ratio of main pulmonary artery di-ameter to descending aorta diameter were significantly lager in mild PH group and moderate_severe PH group ,there were statistically significant differences ( P<0.01 ) ,while FVC ,FEV1 ,FEV1/FVC ,DLCO showed no significant differences ( P>0.05 ).Conclu-sions The main pulmonary artery diameter and the ratio of main pulmonary artery diameter to descending aorta diameter on CT scan can be used to screen for PH.
