CAJ | 학술논문

目的：：探讨D-二聚体、纤维蛋白原(FIB)、癌胚抗原(CEA)水平与小细胞肺癌(SCLC)患者生存期的关系。方法：回顾性分析经病理学确诊的78例SCLC患者的临床资料，分析患者D-二聚体、FIB、CEA水平与生存期的关系。结果：SCLC患者生存期与D-二聚体、FIB、CEA水平有关(P＜0.05)；Cox多因素回归分析结果显示， D-二聚体水平为影响SCLC患者生存期的独立因素(P＜0.05)。结论：D-二聚体、FIB、CEA水平均与SCLC患者生存期有关，其中D-二聚体可作为判定SCLC患者预后的指标。
목적：：탐토D-이취체、섬유단백원(FIB)、암배항원(CEA)수평여소세포폐암(SCLC)환자생존기적관계。방법：회고성분석경병이학학진적78례SCLC환자적림상자료，분석환자D-이취체、FIB、CEA수평여생존기적관계。결과：SCLC환자생존기여D-이취체、FIB、CEA수평유관(P＜0.05)；Cox다인소회귀분석결과현시， D-이취체수평위영향SCLC환자생존기적독립인소(P＜0.05)。결론：D-이취체、FIB、CEA수평균여SCLC환자생존기유관，기중D-이취체가작위판정SCLC환자예후적지표。
[ABSTRACT]Objective: To investigate the relationships between D-dimer, ifbrinogen (FIB), carcino-embryonic antigen (CEA) and survival time in patients with small cell lung cancer (SCLC).Methods: The clinical data of 78 SCLC patients were collected and retrospectively analyzed the relationships between D-dimer, FIB, CEA level and survival time of SCLC patients.Results:The survival time of SCLC patients was connected with D-dimer, FIB and CEA level (P<0.05). Cox regression analysis showed that D-dimer level was an independent factor that inlfuence survival time of SCLC patients (P<0.05).Conclusions: D-dimer, FIB and CEA level are relevant to survival time of SCLC patients. D-dimer level can be used as a prognostic indicator for SCLC patients.