CAJ | 학술논문

目的：对比分析阿奇霉素与清开灵序贯疗法治疗小儿肺炎的临床效果及安全性。方法选取2012年2月至2014年9月我院收治的肺炎患儿162例，随机分为观察组（采用阿奇霉素序贯疗法治疗）和对照组（采用清开灵序贯疗法治疗），每组81例，比较两组有效率、临床症状消失时间、住院时间及不良反应发生情况。结果观察组与对照组比较有效率、胸部影像明显吸收比例均较高，临床症状消失时间及住院时间均较少，差异有统计学意义（P＜0．05），两组不良反应总发生率比较差异无统计学意义（ P＞0．05）。结论肺炎患儿采用阿奇霉素序贯疗法治疗效果显著，优于清开灵序贯疗法治疗，有较高的安全性，可在临床推广应用。
목적：대비분석아기매소여청개령서관요법치료소인폐염적림상효과급안전성。방법선취2012년2월지2014년9월아원수치적폐염환인162례，수궤분위관찰조（채용아기매소서관요법치료）화대조조（채용청개령서관요법치료），매조81례，비교량조유효솔、림상증상소실시간、주원시간급불량반응발생정황。결과관찰조여대조조비교유효솔、흉부영상명현흡수비례균교고，림상증상소실시간급주원시간균교소，차이유통계학의의（P＜0．05），량조불량반응총발생솔비교차이무통계학의의（ P＞0．05）。결론폐염환인채용아기매소서관요법치료효과현저，우우청개령서관요법치료，유교고적안전성，가재림상추엄응용。
Objective This article aimed to compare and analyze the effect and safety of azithromycin and Qingkailing sequential therapy in the treatment of children with pneumonia.Methods 162 cases of childrenpneumonia patients in our hospital during February 2012 and September 2014were selected, they were randomly divided into the observation group ( used azithromycin sequential therapy ) and control group ( used Qingkailing sequential therapy ) , 81 cases of patients in each group. The efficient, time of clinical symptomsdisappearing, hospitalization time and adverse events of the two groups were compared.Results The efficient and chest imaging absorb proportion of the observation group were significantly higher than control group, the time of disappearance of clinical symptoms and hospital stay of observe group were less than that of control group, the differenceswerestatistically significant (P<0.05).The overall incidence of adverse reactions between the two groups was not significant difference (P>0.05).Conclusions Azithromycin sequential therapy in the treatment of children with pneumonia can obtain better efficacy than Qingkailing sequential therapy, so it can be applied in clinical practice.