CAJ | 학술논문

目的：观察重组人表皮生长因子对肛周脓肿患者术后创面愈合的影响。方法随机将112例肛周脓肿手术患者分为治疗组（ n＝56）和对照组（ n＝56）。治疗组：创面用生理盐水消毒，以浸有重组人表皮生长因子凝胶纱条填塞。对照组：常规消毒，用甲硝唑纱条或雷佛奴尔纱条填塞。手术后3、7、10 d观察创面水肿情况及愈合时间。结果治疗组和对照组手术后3、7、10 d创面水肿评分分别为[（1.20±0.70）、（1.00±0.67）、（1.05±0.69）]和[（1.70±0.66）、（1.90±0.74）、（1.70±0.73）]，两组比较差异有统计学意义（ P﹤0.05），两组创面愈合时间比较，差异有统计学意义（ P﹤0.05）。结论重组人表皮生长因子能明显促进创面愈合。
목적：관찰중조인표피생장인자대항주농종환자술후창면유합적영향。방법수궤장112례항주농종수술환자분위치료조（ n＝56）화대조조（ n＝56）。치료조：창면용생리염수소독，이침유중조인표피생장인자응효사조전새。대조조：상규소독，용갑초서사조혹뢰불노이사조전새。수술후3、7、10 d관찰창면수종정황급유합시간。결과치료조화대조조수술후3、7、10 d창면수종평분분별위[（1.20±0.70）、（1.00±0.67）、（1.05±0.69）]화[（1.70±0.66）、（1.90±0.74）、（1.70±0.73）]，량조비교차이유통계학의의（ P﹤0.05），량조창면유합시간비교，차이유통계학의의（ P﹤0.05）。결론중조인표피생장인자능명현촉진창면유합。
Objective To observe the effects of recombinant human epidermal growth factor ( rhEGF)on wound healing of perianal abscess after operation. Methods A total of 112 cases of perianal abscess after operation were randomly divided into the study group( n=56 )and control group( n=56 ). Patients in the control group were disinfected routinely and treated by metronidazole or rivanol. In the stud-y group,patients were treated by rhEGF after disinfection of saline. Wound edema score was evaluated at the 3rd,7th and 10th day after the surgery. Healing time of the wound was recorded simultaneously. Re-sults Wound edema scores in the study group[(1. 20 ± 0. 70),(1. 00 ± 0. 67),and(1. 05 ± 0. 69)] were significantly lower than those of the control group[(1. 70 ± 0. 66),(1. 90 ± 0. 74),and(1. 70 ± 0. 73)]at the 3rd,7th and 10th day after operation(P﹤0. 05). Conclusion rhEGF can promote wound healing obviously.