中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
10期
48-49,50
,共3页
小儿%支原体感染%阿奇霉素
小兒%支原體感染%阿奇黴素
소인%지원체감염%아기매소
Children%Mycoplasma infection%Azithromycin
目的：探讨阿奇霉素采用不同用药方式治疗小儿支原体感染的临床疗效。方法：随机抽取166例本院2013年1-12月收治的小儿支原体感染患儿作为本次研究对象，按随机双盲法分为观察组与对照组，对照组患儿83例，采用常规治疗方法的基础上，首次剂量为20 mg/kg阿奇霉素注射液静脉滴注，持续用药5 d，1次/d，后4 d用药量为首次的一半，停药4 d后，再次治疗3 d。观察组患儿83例其他同上，在患儿停药4 d后，再次治疗5 d。治疗结束后，对两组患儿的临床疗效、住院时间及各种病症消失时间进行比较。结果：观察组患儿的痊愈率及总有效率分别为84.3%（70例）、95.1%（79例），对照组分别为79.5%（66例）、91.5%（76例），两组比较差异无统计学意义。观察组患儿住院时间及各种症状消失时间均低于对照组，比较差异有统计学意义（P<0.05）。结论：采用阿奇霉素对患儿进行静脉滴注治疗5 d后，停药4 d，再次治疗5 d，能有效缩短患儿的住院时间及各种疾病的消失时间，得到了患儿家属的一致好评，值得在临床上进行推广。
目的：探討阿奇黴素採用不同用藥方式治療小兒支原體感染的臨床療效。方法：隨機抽取166例本院2013年1-12月收治的小兒支原體感染患兒作為本次研究對象，按隨機雙盲法分為觀察組與對照組，對照組患兒83例，採用常規治療方法的基礎上，首次劑量為20 mg/kg阿奇黴素註射液靜脈滴註，持續用藥5 d，1次/d，後4 d用藥量為首次的一半，停藥4 d後，再次治療3 d。觀察組患兒83例其他同上，在患兒停藥4 d後，再次治療5 d。治療結束後，對兩組患兒的臨床療效、住院時間及各種病癥消失時間進行比較。結果：觀察組患兒的痊愈率及總有效率分彆為84.3%（70例）、95.1%（79例），對照組分彆為79.5%（66例）、91.5%（76例），兩組比較差異無統計學意義。觀察組患兒住院時間及各種癥狀消失時間均低于對照組，比較差異有統計學意義（P<0.05）。結論：採用阿奇黴素對患兒進行靜脈滴註治療5 d後，停藥4 d，再次治療5 d，能有效縮短患兒的住院時間及各種疾病的消失時間，得到瞭患兒傢屬的一緻好評，值得在臨床上進行推廣。
목적：탐토아기매소채용불동용약방식치료소인지원체감염적림상료효。방법：수궤추취166례본원2013년1-12월수치적소인지원체감염환인작위본차연구대상，안수궤쌍맹법분위관찰조여대조조，대조조환인83례，채용상규치료방법적기출상，수차제량위20 mg/kg아기매소주사액정맥적주，지속용약5 d，1차/d，후4 d용약량위수차적일반，정약4 d후，재차치료3 d。관찰조환인83례기타동상，재환인정약4 d후，재차치료5 d。치료결속후，대량조환인적림상료효、주원시간급각충병증소실시간진행비교。결과：관찰조환인적전유솔급총유효솔분별위84.3%（70례）、95.1%（79례），대조조분별위79.5%（66례）、91.5%（76례），량조비교차이무통계학의의。관찰조환인주원시간급각충증상소실시간균저우대조조，비교차이유통계학의의（P<0.05）。결론：채용아기매소대환인진행정맥적주치료5 d후，정약4 d，재차치료5 d，능유효축단환인적주원시간급각충질병적소실시간，득도료환인가속적일치호평，치득재림상상진행추엄。
Objective: To discuss the clinical curative effect of using different treatment method of azithromycin treatment of children with Mycoplasma infection.Method: 166 patients with mycoplasma infection in our hospital from 2013 January to December were randomly selected as the objects, and randomly divided into observation group and control group, the control group contained 83 cases, which was given treatment of azithromycin based conventional treatment methods: the first dose of 20 mg/kg Azithromycin injection, intravenous infusion of the drug, sustained 5D, 1 time/d, after 4D dosage for the first half, after 4D of withdrawal, again in the treatment of 3D by using this method; the observation group contained 83 cases, which carries on the treatment method using the same control group based on the conventional treatment, difference was that, stop drug 4D in children, again in the treatment of 5D using this method. At the end of treatment, the clinical efficacy, duration of hospitalization, and various symptoms disappear time of the two groups was compared.Result: The cure rate and total effective rate of the observation group was 84.3% (70 cases), 95.1% (79 cases), and that of the control group was 79.5% (66 cases), 91.5% (76 cases), there was no statistically significant difference. The hospitalization time and a variety of diseases disappear time of the observation group was lower than that of the control group, there was statistically significant difference (P<0.05).Conclusion: The use of azithromycin intravenous infusion therapy for children with 5D after stopping drug, 4D, again in the treatment of 5D by using this method, can effectively shorten the symptom disappearance time, get favorable comments from the families of the children, worthy of promotion and application in clinical.
