中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
10期
29-30,31
,共3页
舒芬太尼%咪唑安定%椎管内麻醉
舒芬太尼%咪唑安定%椎管內痳醉
서분태니%미서안정%추관내마취
Sufentanil%Midazolam%Spinal anesthesia
目的：探讨舒芬太尼复合咪唑安定辅助椎管内麻醉的临床效果和应用价值。方法：选择90例择期开腹手术的患者行椎管内麻醉，随机数字表法分两组，每组45例，Ⅰ组为舒芬太尼联合咪唑安定，Ⅱ组为芬太尼联合咪唑安定，比较临床效果。结果：在麻醉诱导后、手术开始、结束时Ⅰ组患者的收缩压、舒张压均明显低于Ⅱ组，比较差异有统计学意义（P<0.05）；Ⅰ组对心率与用药前相比的影响比Ⅱ组大，腹腔进行冲洗和探查时，Ⅰ组有体动反应的出现，且心血管波动幅度不如Ⅱ组明显。SpO2Ⅰ组的相关参数略高于Ⅱ组，且诱导中出现SpO2<93%的患者例数Ⅱ组多于Ⅰ组。结论：作为椎管内麻醉的辅助用药，舒芬太尼复合咪唑安定镇静镇痛和顺行性遗忘作用效果好，起效快，安全且不良反应发生率小。
目的：探討舒芬太尼複閤咪唑安定輔助椎管內痳醉的臨床效果和應用價值。方法：選擇90例擇期開腹手術的患者行椎管內痳醉，隨機數字錶法分兩組，每組45例，Ⅰ組為舒芬太尼聯閤咪唑安定，Ⅱ組為芬太尼聯閤咪唑安定，比較臨床效果。結果：在痳醉誘導後、手術開始、結束時Ⅰ組患者的收縮壓、舒張壓均明顯低于Ⅱ組，比較差異有統計學意義（P<0.05）；Ⅰ組對心率與用藥前相比的影響比Ⅱ組大，腹腔進行遲洗和探查時，Ⅰ組有體動反應的齣現，且心血管波動幅度不如Ⅱ組明顯。SpO2Ⅰ組的相關參數略高于Ⅱ組，且誘導中齣現SpO2<93%的患者例數Ⅱ組多于Ⅰ組。結論：作為椎管內痳醉的輔助用藥，舒芬太尼複閤咪唑安定鎮靜鎮痛和順行性遺忘作用效果好，起效快，安全且不良反應髮生率小。
목적：탐토서분태니복합미서안정보조추관내마취적림상효과화응용개치。방법：선택90례택기개복수술적환자행추관내마취，수궤수자표법분량조，매조45례，Ⅰ조위서분태니연합미서안정，Ⅱ조위분태니연합미서안정，비교림상효과。결과：재마취유도후、수술개시、결속시Ⅰ조환자적수축압、서장압균명현저우Ⅱ조，비교차이유통계학의의（P<0.05）；Ⅰ조대심솔여용약전상비적영향비Ⅱ조대，복강진행충세화탐사시，Ⅰ조유체동반응적출현，차심혈관파동폭도불여Ⅱ조명현。SpO2Ⅰ조적상관삼수략고우Ⅱ조，차유도중출현SpO2<93%적환자례수Ⅱ조다우Ⅰ조。결론：작위추관내마취적보조용약，서분태니복합미서안정진정진통화순행성유망작용효과호，기효쾌，안전차불량반응발생솔소。
Objective: To investigate the effect of sufentanil midazolam intraspinal anesthesia clinical effect and application value.Method: In our hospital 90 elective abdominal operation patients with intraspinal anesthesia, were randomly divided into two groups, 45 cases in each group, Ⅰ group sufentanil combined with midazolam, Ⅱ group and fentanyl combined with midazolam, analyze clinical effect of the two groups.Result: After induction of anesthesia, operation began, at the end of Ⅰ group patients with systolic blood pressure, diastolic blood pressure were significantly lower than that of the Ⅱ group, the difference was statistically significant (P<0.05). Analgesic and sedative effect of the Ⅰ group than that of the Ⅱ group, the Ⅱ group to maintain the dosage was small, the onset time of the Ⅰ group than in the Ⅱ group quickly, adverse reaction and inhibition of respiratory complications were less than the Ⅱ group, in the wash and exploration on the abdominal cavity, Ⅰ group had the body movement, and cardiovascular fluctuations than the Ⅱ group was significantly.Conclusion: As adjuvant of spinal anesthesia, the composite sufentanil midazolam sedation and anterograde amnesia effect is good, fast, safe and adverse reaction rate.
