中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2015年
2期
121-124
,共4页
赵宪孟%郭玉强%韩二营%张清生%李月礼%赵春凤%景桂莲
趙憲孟%郭玉彊%韓二營%張清生%李月禮%趙春鳳%景桂蓮
조헌맹%곽옥강%한이영%장청생%리월례%조춘봉%경계련
视网膜病变,糖尿病性,增生性%玻璃体切除术%曲安奈德,半量
視網膜病變,糖尿病性,增生性%玻璃體切除術%麯安奈德,半量
시망막병변,당뇨병성,증생성%파리체절제술%곡안내덕,반량
Retinopathy,diabetic,proliferative%Vitrectomy%Triamcinolone acetonide,half-dose
目的 探讨玻璃体切除术联合半量曲安奈德(triamcinolone acetonide)玻璃体内注射治疗增生性糖尿病视网膜病变疗效和安全性.方法 回顾性分析增生性糖尿病视网膜病变32例(39眼)经玻璃体切除术联合半量曲安奈德(2 mg/0.05 ml)玻璃体内注射的临床资料,术中根据病情进行剥膜、眼内激光、巩膜外冷凝、硅油或C3F8填充.术后观察视力、眼压、前房炎症反应、晶状体浑浊、有无玻璃体视网膜出血及视网膜脱离情况.结果 随访3 ～18月,平均(7.81 ±4.52)月,36眼(92.31％)术后视力有不同程度的提高,术后视力与术前相比差异有统计学意义(z=-5.539,P=3.03×10-8).术后3个月眼压与术前眼压差异无统计学意义(t=-0.204,P=0.84).术后2周内发生一过性高眼压8眼(20.51％),通过降眼压药物治疗,眼压恢复正常.前房有轻度炎症反应,白内障8眼(20.51％),视网膜脱离2眼(5.13％).结论 玻璃体切除术联合半量曲安奈德玻璃体内注射是治疗增生性糖尿病视网膜病变安全、有效的方法,能控制眼内炎症,改善视力,严重并发症较少发生.
目的 探討玻璃體切除術聯閤半量麯安奈德(triamcinolone acetonide)玻璃體內註射治療增生性糖尿病視網膜病變療效和安全性.方法 迴顧性分析增生性糖尿病視網膜病變32例(39眼)經玻璃體切除術聯閤半量麯安奈德(2 mg/0.05 ml)玻璃體內註射的臨床資料,術中根據病情進行剝膜、眼內激光、鞏膜外冷凝、硅油或C3F8填充.術後觀察視力、眼壓、前房炎癥反應、晶狀體渾濁、有無玻璃體視網膜齣血及視網膜脫離情況.結果 隨訪3 ～18月,平均(7.81 ±4.52)月,36眼(92.31％)術後視力有不同程度的提高,術後視力與術前相比差異有統計學意義(z=-5.539,P=3.03×10-8).術後3箇月眼壓與術前眼壓差異無統計學意義(t=-0.204,P=0.84).術後2週內髮生一過性高眼壓8眼(20.51％),通過降眼壓藥物治療,眼壓恢複正常.前房有輕度炎癥反應,白內障8眼(20.51％),視網膜脫離2眼(5.13％).結論 玻璃體切除術聯閤半量麯安奈德玻璃體內註射是治療增生性糖尿病視網膜病變安全、有效的方法,能控製眼內炎癥,改善視力,嚴重併髮癥較少髮生.
목적 탐토파리체절제술연합반량곡안내덕(triamcinolone acetonide)파리체내주사치료증생성당뇨병시망막병변료효화안전성.방법 회고성분석증생성당뇨병시망막병변32례(39안)경파리체절제술연합반량곡안내덕(2 mg/0.05 ml)파리체내주사적림상자료,술중근거병정진행박막、안내격광、공막외냉응、규유혹C3F8전충.술후관찰시력、안압、전방염증반응、정상체혼탁、유무파리체시망막출혈급시망막탈리정황.결과 수방3 ～18월,평균(7.81 ±4.52)월,36안(92.31％)술후시력유불동정도적제고,술후시력여술전상비차이유통계학의의(z=-5.539,P=3.03×10-8).술후3개월안압여술전안압차이무통계학의의(t=-0.204,P=0.84).술후2주내발생일과성고안압8안(20.51％),통과강안압약물치료,안압회복정상.전방유경도염증반응,백내장8안(20.51％),시망막탈리2안(5.13％).결론 파리체절제술연합반량곡안내덕파리체내주사시치료증생성당뇨병시망막병변안전、유효적방법,능공제안내염증,개선시력,엄중병발증교소발생.
Objective To investigate the efficacy and safety of pars plana vitrectomy (PPV) combined with intraviteal injection of half-dose triamcinolone acetonide (TA) for proliferative diabetic retinopathy (PDR).Methods Thirty-nine eyes of 32 patients with PDR accepted PPV combined with intraviteal injection of half-dose TA (2 mg/0.05 ml).And membrane peeling,retinal photocoagulation,scleral cryocoagulation,silicone oil or C3F8 gas tamponade were applied according to particular situation respectively.The visual acuity,intraocular pressure (IOP),inflammatory reaction of anterior chamber,lens opacification,vitreoretinal hemorrhage and detachment of retina were observed and analyzed after the procedure.Results Postoperative following up was 3 ～ 18 months,with average (7.81 ±4.52) months.The visual acuity was improved in 36 eyes (92.31％),and the difference was statistically significant between the preoperative one and the postoperative one (Z =-5.539,P =3.03 × 10-8).The difference between the preoperative IOP and the postoperative lOP 3rd month postoperatively was not statistically significant (t =-0.204,P =0.84).Transient postoperative elevated IOP occurred in 8 eyes (20.51％) in two weeks after surgery.All cases had mild inflammatory reaction of anterior chamber.Cataract appeared in 8 eyes (20.51％).And retinal detachment occurred in 2 eyes (5.13％).Conclusion PPV combined with intraviteal injection of half-dose TA is safe and effective for the treatment of PDR.It could control inflammation and improve visual acuity with few serious complications.
