中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2015年
2期
107-111
,共5页
张贵华%陈伟奇%陈浩宇%林杜生%郑建龙
張貴華%陳偉奇%陳浩宇%林杜生%鄭建龍
장귀화%진위기%진호우%림두생%정건룡
超声乳化吸出术%玻璃体切除术%细胞,角膜内皮%视网膜脱离,孔源性
超聲乳化吸齣術%玻璃體切除術%細胞,角膜內皮%視網膜脫離,孔源性
초성유화흡출술%파리체절제술%세포,각막내피%시망막탈리,공원성
Phacoemulsification%Vitrectomy%Cell,corneal enndothelial%Detachment,retinal,rhegmatogenous
目的 探讨孔源性视网膜脱离行超声乳化联合玻璃体切除术对角膜内皮细胞的影响.方法 回顾性分析2010年5月至2012年8月在我院行晶状体超声乳化联合玻璃体切除术治疗孔源性视网膜脱离137例的资料.分别于术前及术后3个月进行角膜内皮镜等检查,比较后囊完整组与后囊破裂组的角膜内皮细胞丢失率,并比较后囊完整时全氟丙烷(C3F8)填充组与硅油填充组术后角膜内皮细胞丢失率.采用多元回归分析患者的年龄、性别、超声乳化绝对时间、手术时间、后囊状态及眼内填充物与角膜内皮细胞丢失率的相关性.结果 各组术后角膜内皮细胞密度均较术前明显减少(P＜0.01),角膜内皮细胞平均丢失率为(12.13±9.91)％.后囊破裂组术后角膜内皮细胞丢失率为(16.68 ±11.04)％,高于后囊完整组的(11.16±9.43)％,P＜0.05);后囊完整时C3F8填充组与硅油填充组术后角膜内皮细胞丢失率差别无统计学意义(P＞0.05).多元回归分析显示超声乳化绝对时间越长,手术时间越长,角膜内皮细胞丢失率越高.结论 晶状体超声乳化联合玻璃体切除术治疗孔源性视网膜脱离可引起患者术后角膜内皮细胞丢失.减少超声乳化绝对时间、手术时间及保持晶状体后囊完整性可以减少角膜内皮细胞的丢失.后囊完整时,玻璃体腔填充物的性质对角膜内皮细胞丢失率没有影响.
目的 探討孔源性視網膜脫離行超聲乳化聯閤玻璃體切除術對角膜內皮細胞的影響.方法 迴顧性分析2010年5月至2012年8月在我院行晶狀體超聲乳化聯閤玻璃體切除術治療孔源性視網膜脫離137例的資料.分彆于術前及術後3箇月進行角膜內皮鏡等檢查,比較後囊完整組與後囊破裂組的角膜內皮細胞丟失率,併比較後囊完整時全氟丙烷(C3F8)填充組與硅油填充組術後角膜內皮細胞丟失率.採用多元迴歸分析患者的年齡、性彆、超聲乳化絕對時間、手術時間、後囊狀態及眼內填充物與角膜內皮細胞丟失率的相關性.結果 各組術後角膜內皮細胞密度均較術前明顯減少(P＜0.01),角膜內皮細胞平均丟失率為(12.13±9.91)％.後囊破裂組術後角膜內皮細胞丟失率為(16.68 ±11.04)％,高于後囊完整組的(11.16±9.43)％,P＜0.05);後囊完整時C3F8填充組與硅油填充組術後角膜內皮細胞丟失率差彆無統計學意義(P＞0.05).多元迴歸分析顯示超聲乳化絕對時間越長,手術時間越長,角膜內皮細胞丟失率越高.結論 晶狀體超聲乳化聯閤玻璃體切除術治療孔源性視網膜脫離可引起患者術後角膜內皮細胞丟失.減少超聲乳化絕對時間、手術時間及保持晶狀體後囊完整性可以減少角膜內皮細胞的丟失.後囊完整時,玻璃體腔填充物的性質對角膜內皮細胞丟失率沒有影響.
목적 탐토공원성시망막탈리행초성유화연합파리체절제술대각막내피세포적영향.방법 회고성분석2010년5월지2012년8월재아원행정상체초성유화연합파리체절제술치료공원성시망막탈리137례적자료.분별우술전급술후3개월진행각막내피경등검사,비교후낭완정조여후낭파렬조적각막내피세포주실솔,병비교후낭완정시전불병완(C3F8)전충조여규유전충조술후각막내피세포주실솔.채용다원회귀분석환자적년령、성별、초성유화절대시간、수술시간、후낭상태급안내전충물여각막내피세포주실솔적상관성.결과 각조술후각막내피세포밀도균교술전명현감소(P＜0.01),각막내피세포평균주실솔위(12.13±9.91)％.후낭파렬조술후각막내피세포주실솔위(16.68 ±11.04)％,고우후낭완정조적(11.16±9.43)％,P＜0.05);후낭완정시C3F8전충조여규유전충조술후각막내피세포주실솔차별무통계학의의(P＞0.05).다원회귀분석현시초성유화절대시간월장,수술시간월장,각막내피세포주실솔월고.결론 정상체초성유화연합파리체절제술치료공원성시망막탈리가인기환자술후각막내피세포주실.감소초성유화절대시간、수술시간급보지정상체후낭완정성가이감소각막내피세포적주실.후낭완정시,파리체강전충물적성질대각막내피세포주실솔몰유영향.
Objective To investigate the effect of combined phacoemulsification and vitrectomy on corneal endothelial cells in rhegmatogenous retinal detachment.Methods The data of 137 rhegmatogenous retinal detachment patients who received combined phacoemulsification and vitrectomy between May 2010 and August 2012 was retrospectively analysed.Corneal endothelial cell density was examined preoperatively and 3 months postoperatively.The loss rate of corneal endothelial cells was compared between posterior capsule intact group and posterior capsule rupture group.It was also compared between C3F8 tamponade group and silicone oil tamponade group when the posterior capsule kept intact after combined surgery; and the correlation between the age,gender,absolute phaco time,operation time,posterior capsule status,tamponade material and the loss rate of corneal endothelial cells were analyzed by multiple regression.Results The comeal endothelial cell density was significantly decreased in all groups after combined phacoemulsification and vitrectomy(P ＜0.01),and the average percentage of endothelial loss was (12.13 ± 9.91)％.The loss rate of endothelial cell was (16.68 ± 11.04)％ in posterior capsule rupture group,which was significantly higher than the percentage of endothelial loss (11.16 ± 9.43) ％ in posterior capsule intact group(P ＜ 0.05).There was no statistically significant difference in the loss rate of corneal endothelial cells between C3 F8 tamponade group and silicone oil tamponade group when the posterior capsule kept intact after combined surgery(P ＞0.05).The positive correlation was detected between the absolute phaco time,operation time and the loss rate of corneal endothelial cells.Conclusion Combined phacoemulsification and vitrectomy can damage the corneal endothelial cells.The percentage of endothelial loss can be decreased by keeping posterior capsule intact,reducing absolute phaco time and reducing operation time.There is no significant difference in the loss rate of corneal endothelial cells between tamponades when the posterior capsule keep intact after combined surgery.
