中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2015年
2期
142-146
,共5页
李科%林国桢%周琴%吴娴波
李科%林國楨%週琴%吳嫻波
리과%림국정%주금%오한파
甲状腺肿瘤%流行病学%发病率%横断面研究
甲狀腺腫瘤%流行病學%髮病率%橫斷麵研究
갑상선종류%류행병학%발병솔%횡단면연구
Thyroid neoplasms%Epidemiology%Incidence%Cross-sectional studies
目的 分析2000-2011年广州市城区甲状腺癌的发病情况及变化趋势.方法 利用广州市肿瘤登记处2000-2011年广州市城区甲状腺癌的发病和人口资料,共计2 957例,覆盖人口45 699 522人年,其中男性649例,覆盖人口23 391 743人年,女性2 308例,覆盖人口22 307 779人年,计算分析不同年度、年龄段的粗发病率、中国人口结构标化发病率(中标发病率)、世界人口构成标化发病率(世标发病率)和发病年度变化百分比(APC),分析各性别和年龄段发病率的变化趋势.结果 2000-2011年广州市城区居民甲状腺癌发病共2 957例,男女发病患者例数比为1∶3.56,世标发病率从2000年的2.99/10万上升到2011年9.13/10万,增加了204.73％,APC为10.5％(P＜0.001);男性的世标发病率从2000年的1.32/10万上升到2011年的3.54/10万,增加了169.45％,APC为8.6％(P＜0.001);女性世标发病率从2000年的4.73/10万上升到2011年的14.87/10万,增加了214.64％,APC为10.9％ (P ＜0.001).男性和女性甲状腺癌发病年龄有较大差别,女性45～59岁为发病高峰,为19.56/10万,男性发病率则随着年龄增长逐步增加,由15 ～ 19岁的0.74/10万增加到85岁以上组的9.48/10万.20 ～59岁年龄组男、女性APC分别为12.2％、13.4％,差异均有统计学意义(P＜0.001).结论 甲状腺癌发病呈逐年上升趋势,20 ～ 59岁年龄组人群是甲状腺癌防治的重点人群.
目的 分析2000-2011年廣州市城區甲狀腺癌的髮病情況及變化趨勢.方法 利用廣州市腫瘤登記處2000-2011年廣州市城區甲狀腺癌的髮病和人口資料,共計2 957例,覆蓋人口45 699 522人年,其中男性649例,覆蓋人口23 391 743人年,女性2 308例,覆蓋人口22 307 779人年,計算分析不同年度、年齡段的粗髮病率、中國人口結構標化髮病率(中標髮病率)、世界人口構成標化髮病率(世標髮病率)和髮病年度變化百分比(APC),分析各性彆和年齡段髮病率的變化趨勢.結果 2000-2011年廣州市城區居民甲狀腺癌髮病共2 957例,男女髮病患者例數比為1∶3.56,世標髮病率從2000年的2.99/10萬上升到2011年9.13/10萬,增加瞭204.73％,APC為10.5％(P＜0.001);男性的世標髮病率從2000年的1.32/10萬上升到2011年的3.54/10萬,增加瞭169.45％,APC為8.6％(P＜0.001);女性世標髮病率從2000年的4.73/10萬上升到2011年的14.87/10萬,增加瞭214.64％,APC為10.9％ (P ＜0.001).男性和女性甲狀腺癌髮病年齡有較大差彆,女性45～59歲為髮病高峰,為19.56/10萬,男性髮病率則隨著年齡增長逐步增加,由15 ～ 19歲的0.74/10萬增加到85歲以上組的9.48/10萬.20 ～59歲年齡組男、女性APC分彆為12.2％、13.4％,差異均有統計學意義(P＜0.001).結論 甲狀腺癌髮病呈逐年上升趨勢,20 ～ 59歲年齡組人群是甲狀腺癌防治的重點人群.
목적 분석2000-2011년엄주시성구갑상선암적발병정황급변화추세.방법 이용엄주시종류등기처2000-2011년엄주시성구갑상선암적발병화인구자료,공계2 957례,복개인구45 699 522인년,기중남성649례,복개인구23 391 743인년,녀성2 308례,복개인구22 307 779인년,계산분석불동년도、년령단적조발병솔、중국인구결구표화발병솔(중표발병솔)、세계인구구성표화발병솔(세표발병솔)화발병년도변화백분비(APC),분석각성별화년령단발병솔적변화추세.결과 2000-2011년엄주시성구거민갑상선암발병공2 957례,남녀발병환자례수비위1∶3.56,세표발병솔종2000년적2.99/10만상승도2011년9.13/10만,증가료204.73％,APC위10.5％(P＜0.001);남성적세표발병솔종2000년적1.32/10만상승도2011년적3.54/10만,증가료169.45％,APC위8.6％(P＜0.001);녀성세표발병솔종2000년적4.73/10만상승도2011년적14.87/10만,증가료214.64％,APC위10.9％ (P ＜0.001).남성화녀성갑상선암발병년령유교대차별,녀성45～59세위발병고봉,위19.56/10만,남성발병솔칙수착년령증장축보증가,유15 ～ 19세적0.74/10만증가도85세이상조적9.48/10만.20 ～59세년령조남、녀성APC분별위12.2％、13.4％,차이균유통계학의의(P＜0.001).결론 갑상선암발병정축년상승추세,20 ～ 59세년령조인군시갑상선암방치적중점인군.
Objective To investigate the incidence and trends of thyroid cancer in urban areas of Guangzhou,2000-2011.Methods Total of 2 957 new cases with a coverage population of 45 699 522 person-years diagnosed as thyroid cancer in 2000-2011 in urban areas of Guangzhou were extracted from the population-based data base of Guangzhou cancer registry,among which 649 were males and 2 308 were females with a coverage population of 23 391 743 person-years and 22 307 779 person-years,respectively.The crude incidence,Chinese age-adjusted incidence rate and world age-adjusted incidence rate were calculated.Time trends of different gender and age groups were examined using Joinpoint Regression Program.Results There were a total of 2 957 cases diagnosed as thyroid cancer during 2000-2011 with a sex ratio of 1 ∶ 3.56.World age adjusted incidence rates of thyroid cancer in urban areas of Guangzhou increased dramatically from 2.99/100 000 in 2000 to 9.13/100 000 in 2011 with an increase rate of 204.73％.Annual percentage change(APC)was 10.5％ (P ＜ 0.001).The APC in world age adjusted incidence rates of thyroid cancer were 8.6％ (P ＜ 0.001) for male and 10.9％ (P ＜ 0.001) for female,resulting in a total increase of 169.45％ (from 1.32/100 000 to 3.54/100 000) for male and 214.64％ for female(from 4.73/100 000 to 14.87/100 000).The mean age of onset of thyroid cancer was significantly different between the males and females.The incidence rate of thyroid cancer in females aged 45-59 group (19.56/100 000) reached the highest one.While in males,it was increasing gradually with the age,the incidence increased from 0.74/100 000 in aged 15-19 to 9.48/10 000 in aged of 85 years above.The APC was significant in 20-59 age groups in both males (12.2％) and females (13.4％) (P ＜ 0.001).Conclusions The incidence rate of thyroid cancer increased rapidly in urban areas of Guangzhou.The prevention and treatment of thyroid cancer should be focused on 20-59 age groups.
