CAJ | 학술논문

目的：探讨不同剂量右美托咪啶防治腰硬联合麻醉剖宫产术中寒战的效果。方法60例腰硬联合麻醉下行剖宫产术产妇，随机分为3组：右美托咪啶1组（D1组），右美托咪啶2组（D2组），对照组（C组）。胎儿取出即刻，D1、D2组分别于10min内泵注0.5μg/kg、1.0μg/kg右美托咪啶；对照组泵入10ml生理盐水。观察注药时（T0）、注药后5min（T1）、腹腔探查时（T2）、手术结束时（T3）的平均动脉压（MBP）、血氧饱和度（SpO2）、心率（HR）、术中寒战发生例数以及术后不良反应。结果与C组比较，D1、D2组寒战发生率明显降低（P＜0.05），D1组用药后不良反应比D2组发生率低（P＜0.05）。结论0.5μg/kg右美托咪啶静脉注射能够有效防治剖宫产术中寒战的发生，且不良反应少。
목적：탐토불동제량우미탁미정방치요경연합마취부궁산술중한전적효과。방법60례요경연합마취하행부궁산술산부，수궤분위3조：우미탁미정1조（D1조），우미탁미정2조（D2조），대조조（C조）。태인취출즉각，D1、D2조분별우10min내빙주0.5μg/kg、1.0μg/kg우미탁미정；대조조빙입10ml생리염수。관찰주약시（T0）、주약후5min（T1）、복강탐사시（T2）、수술결속시（T3）적평균동맥압（MBP）、혈양포화도（SpO2）、심솔（HR）、술중한전발생례수이급술후불량반응。결과여C조비교，D1、D2조한전발생솔명현강저（P＜0.05），D1조용약후불량반응비D2조발생솔저（P＜0.05）。결론0.5μg/kg우미탁미정정맥주사능구유효방치부궁산술중한전적발생，차불량반응소。
Objective To investigate the effect on the prevention of shivering in spinal-epidural anesthesia by different dose of dexmedetomidine during cesarean section. Methods 60 cases of spinal-epidural anesthesia accepted cesarean section parturients were randomly divided into three groups: dexmedetomidine group 1 (group D1), dexmedetomidine group 2 (group D2), control group (group C). As soon as fetus was removed, 0.5μg/kg and 1.0μg/kg dexmedetomidine were infused in group D1 and D2 in 10 minutes respectively. Group C was pumped into 10ml physiological saline. Mean arterial pressure (MBP), blood oxygen saturation(SpO2), heart rate (HR), the incidence of shivering during operation, postoperative adverse reaction were ob-served at drug injection time (T0), 5 minutes after injection (T1), abdominal exploration time (T2) and the end of operation (T3). Results Compared with group C, group D1 and D2 significantly reduced the incidence of shivering (P<0.05), the drug adverse reaction incidence of group D1 was lower than that in group D2 (P<0.05). Conclusion 0.5μg/kg dexmedetomidine intravenous injection can effectively prevent and control the shivering during cesarean section, and has less adverse reaction.