CAJ | 학술논문

目的：探讨血清降钙素原（PCT）在鉴别儿童急性阑尾炎及肠系膜淋巴结炎中的意义。方法回顾性分析2008年7月至2013年7月我们收治的儿童急性阑尾炎（为阑尾炎组）和急性肠系膜淋巴结炎（为肠系膜淋巴结炎组）患儿临床资料。其中阑尾炎组42例，急性肠系膜淋巴结炎组36例，比较两组治疗前后 PCT、C —反应蛋白（CRP）和白细胞计数（WBC），以及这三种指标诊断的特异性、敏感性、阳性预测值和阴性预测值。结果治疗前急性阑尾炎组 PCT 检测结果明显高于正常值，而急性肠系膜淋巴结炎组 PCT 检测结果基本正常，且两组差异有显著统计学意义（P ＜0．01）；治疗3 d 后两组PCT 检测结果均基本正常，差异无统计学意义（P ＞0．05）；以 PCT ＞0．5 ng／mL 作为诊断指标时，特异性、敏感性、阳性预测值、阴性预测值均高于 CRP 及 WBC。结论早期检测 PCT 有助于儿童急性阑尾炎与肠系膜淋巴结炎的鉴别诊断。
목적：탐토혈청강개소원（PCT）재감별인동급성란미염급장계막림파결염중적의의。방법회고성분석2008년7월지2013년7월아문수치적인동급성란미염（위란미염조）화급성장계막림파결염（위장계막림파결염조）환인림상자료。기중란미염조42례，급성장계막림파결염조36례，비교량조치료전후 PCT、C —반응단백（CRP）화백세포계수（WBC），이급저삼충지표진단적특이성、민감성、양성예측치화음성예측치。결과치료전급성란미염조 PCT 검측결과명현고우정상치，이급성장계막림파결염조 PCT 검측결과기본정상，차량조차이유현저통계학의의（P ＜0．01）；치료3 d 후량조PCT 검측결과균기본정상，차이무통계학의의（P ＞0．05）；이 PCT ＞0．5 ng／mL 작위진단지표시，특이성、민감성、양성예측치、음성예측치균고우 CRP 급 WBC。결론조기검측 PCT 유조우인동급성란미염여장계막림파결염적감별진단。
Objective To investigate the evaluation of procalcitonin in the diagnostic value of acute ap-pendicitis and mesenteric lymphadenitis in child.Methods The clinical data of acute appendicitis and mesen-teric lymphadenitis in children from July.2008 to July.2013 were reviewed.They were divided into the appen-dicitis group of 42 cases and the mesenteric lymphadenitis group of 36 cases.The detection results of PCT、CRP、WBC before and after treatment were compared.Meanwhile,the specificity,sensitivity,positive and nega-tive predictive value were compared.Results PCT of the acute appendicitis group was higher than that of the mesenteric lymphadenitis group before the treatment (P <0.01).while,there were,not significant difference between them after 3 days of the treatment (P >0.05).When PCT(>0.5 ng/mL)was used as a diagnostic indicator,specificity,sensitivity,positive and negative predictive value were higher than CRP and WBC. Con-clusions Early detection of PCT are helpful to differential diagnosis between acute appendicitis and mesenteric lymphadenitis in children.