CAJ | 학술논문

目前对内皮祖细胞的研究重点更多是在冠心病的治疗作用中。雌激素对冠心病的病理生理及预后可能均有影响，针对它的保护作用仍在不断的研究。目前有大量证据提示雌激素可以通过促进内皮祖细胞的增殖、分化、迁移、减少凋亡，来增加内皮修复、损伤区域侧支循环的建立及血管新生，从而改善心肌梗死后的症状、缩小梗死灶的治疗效果，最终改善心脏功能。目前内皮祖细胞对冠心病全面作用尚缺乏研究，雌激素在冠心病的预防和治疗中的有益作用也需要更多的研究来证实。
목전대내피조세포적연구중점경다시재관심병적치료작용중。자격소대관심병적병리생리급예후가능균유영향，침대타적보호작용잉재불단적연구。목전유대량증거제시자격소가이통과촉진내피조세포적증식、분화、천이、감소조망，래증가내피수복、손상구역측지순배적건립급혈관신생，종이개선심기경사후적증상、축소경사조적치료효과，최종개선심장공능。목전내피조세포대관심병전면작용상결핍연구，자격소재관심병적예방화치료중적유익작용야수요경다적연구래증실。
At present the research emphasis on endothelial progenitor cells is more effect in the treat-ment of coronary heart disease .Estrogen to the physiological pathology and prognosis of coronary heart disease may have effect ,for it continues to study the protective effects of .There are a lot of evidence to suggest that es-trogen can promote endothelial progenitor cell proliferation ,differentiation ,migration and apoptosis ,to increase endothelial repair ,and damage the establishment of collateral circulation and angiogenesis ,so as to improve the symptoms of myocardial infarction ,the therapeutic effect of smaller infarcts ,eventually improve the heart func-tion .Endothelial progenitor cells of coronary heart disease (CHD) is still a lack of research ,the beneficial effects of estrogen on the prevention and treatment of coronary heart disease and more research is needed to confirm .