中国医学装备
中國醫學裝備
중국의학장비
CHINA MEDICAL EQUIPMENT
2015年
4期
102-104,105
,共4页
王晗%何叶莉%谢娜%耿伟%李妍%杨宁%李沛然%郭桐生%朱剑功%毛远丽
王晗%何葉莉%謝娜%耿偉%李妍%楊寧%李沛然%郭桐生%硃劍功%毛遠麗
왕함%하협리%사나%경위%리연%양저%리패연%곽동생%주검공%모원려
尿沉渣%细菌感染%降钙素原%C反应蛋白
尿沉渣%細菌感染%降鈣素原%C反應蛋白
뇨침사%세균감염%강개소원%C반응단백
Urinary sediment%Bacterial infection%Procalcitonin%C reactive protein
目的：探讨LabUMat尿沉渣工作站尿液白细胞数(LEU)、细菌定量计数(BAC)、粘液丝(MUC)等指标在尿路感染中的诊断价值。方法：应用LabUMat尿沉渣工作站检测292例肝病患者尿液中LEU、BAC和MUC水平，并采用电化学发光免疫分析法和酶法检测血清降钙素原(PCT)、C反应蛋白(CRP)、直接胆红素(DBIL)、总胆红素(TBIL)和谷丙转氨酶(ALT)水平。以尿液细菌培养结果为金标准，评价LEU、BAC和MUC在尿路感染时变化特点及诊断价值。结果：肝病患者尿路感染以G-菌感染为主占80.5%，大肠埃希菌是主要致病菌，G+菌以屎肠球菌居多。以细菌培养结果为金标准，BAC在尿路感染诊断价值ROC面积为0.82，灵敏度为77.83%，特异度为90.2%；LEU ROC面积为0.85，灵敏度为87.6%，特异度为83.3%；MUC ROC面积为0.63，灵敏度为60.3%，特异度为72.7%。随着BAC水平的不断升高，尿LEU、MUC和血PCT、DBIL、TBIL水平均出现显著升高(t=13.8，t=12.3，t=4.5，t=15.2，t=11.6；和t=16.7，t=17.1，t=10.8，t=20.3，t=19.6；P＜0.01)。结论：LabUMat尿沉渣工作站对辅助诊断尿路感染具有较高价值。
目的：探討LabUMat尿沉渣工作站尿液白細胞數(LEU)、細菌定量計數(BAC)、粘液絲(MUC)等指標在尿路感染中的診斷價值。方法：應用LabUMat尿沉渣工作站檢測292例肝病患者尿液中LEU、BAC和MUC水平，併採用電化學髮光免疫分析法和酶法檢測血清降鈣素原(PCT)、C反應蛋白(CRP)、直接膽紅素(DBIL)、總膽紅素(TBIL)和穀丙轉氨酶(ALT)水平。以尿液細菌培養結果為金標準，評價LEU、BAC和MUC在尿路感染時變化特點及診斷價值。結果：肝病患者尿路感染以G-菌感染為主佔80.5%，大腸埃希菌是主要緻病菌，G+菌以屎腸毬菌居多。以細菌培養結果為金標準，BAC在尿路感染診斷價值ROC麵積為0.82，靈敏度為77.83%，特異度為90.2%；LEU ROC麵積為0.85，靈敏度為87.6%，特異度為83.3%；MUC ROC麵積為0.63，靈敏度為60.3%，特異度為72.7%。隨著BAC水平的不斷升高，尿LEU、MUC和血PCT、DBIL、TBIL水平均齣現顯著升高(t=13.8，t=12.3，t=4.5，t=15.2，t=11.6；和t=16.7，t=17.1，t=10.8，t=20.3，t=19.6；P＜0.01)。結論：LabUMat尿沉渣工作站對輔助診斷尿路感染具有較高價值。
목적：탐토LabUMat뇨침사공작참뇨액백세포수(LEU)、세균정량계수(BAC)、점액사(MUC)등지표재뇨로감염중적진단개치。방법：응용LabUMat뇨침사공작참검측292례간병환자뇨액중LEU、BAC화MUC수평，병채용전화학발광면역분석법화매법검측혈청강개소원(PCT)、C반응단백(CRP)、직접담홍소(DBIL)、총담홍소(TBIL)화곡병전안매(ALT)수평。이뇨액세균배양결과위금표준，평개LEU、BAC화MUC재뇨로감염시변화특점급진단개치。결과：간병환자뇨로감염이G-균감염위주점80.5%，대장애희균시주요치병균，G+균이시장구균거다。이세균배양결과위금표준，BAC재뇨로감염진단개치ROC면적위0.82，령민도위77.83%，특이도위90.2%；LEU ROC면적위0.85，령민도위87.6%，특이도위83.3%；MUC ROC면적위0.63，령민도위60.3%，특이도위72.7%。수착BAC수평적불단승고，뇨LEU、MUC화혈PCT、DBIL、TBIL수평균출현현저승고(t=13.8，t=12.3，t=4.5，t=15.2，t=11.6；화t=16.7，t=17.1，t=10.8，t=20.3，t=19.6；P＜0.01)。결론：LabUMat뇨침사공작참대보조진단뇨로감염구유교고개치。
Objective: To investigate the application value of urinary sediment workstation with the index of LEU, BAC, MUC in diagnosis of urinary tract infection. Methods:The levels of LEU, BAC and MUC from urine of 292 patients with hepatitis were detected by LabUMat urinary sediment workstation. The serum levels of PCT, CRP, DBIL, TBIL and ALT were detected by electrochemical luminescence methods and Immunoturbidimetric assays individually. Taking bacterial culture results as gold standard, the changing characterized and diagnostic value of LEU, BAC and MUC were evaluated. Results: Gram-negative bacteria of urine infection were the most common bacteria which accounted for 80.5%, while Escherichia coli took the most. And for Gram-positive bacteria Enterococcus faecium was the most common bacteria. Based on the gold standard of the bacteria cultures, the area under the receiver operating curve(AUC) of BAC was 0.82, and the sensitivity, specificity were 77.83%and 90.2%individually. The AUC of LEU was 0.85, and the sensitivity, specificity were 87.6%and 83.3%individually. The AUC of MUC was 0.63, and the sensitivity, specificity were 60.3%and 72.7%individually. With the rising levels of urinary BAC, the levels of LEU, MUC and PCT, DBIL, TBIL were significantly elevated(t=13.8, t=12.3, t=4.5, t=15.2, t=11.6; and t=16.7, t=17.1, t=10.8, t=20.3, t=19.6, P<0.01). Conclusion:LabUMat Urinary Sediment Workstation had a high value in diagnosis of urinary tract infection.
