CAJ | 학술논문

目的：观察应用白细胞过滤器滤除白细胞输血减少发热性非溶血性输血反应(FNHTR)的临床效果。方法：选择234例患者，按时间段和输血方式的不同将其分为过滤组和对照组。2013年1月至2014年7月采用白细胞过滤器输血的168例患者为过滤组；2011年5月至2012年12月采用普通一次性输血器直接输血的166例患者为对照组。观察比较两组患者FNHTR的发生率。结果：①过滤组输血后体温平均升高(0.46±0.67)℃，对照组输血后体温平均升高(1.38±0.79)℃，对照组体温升高值明显高于过滤组，两组差异比较有统计学意义(P＜0.05)；②过滤组发生FNHTR 20例，发生率为11.11%，对照组发生FNHTR42例，发生率为27.81%,两组FNHTR发生率相比较，其差异有统计学意义(x2=14.90，P＜0.01)。随着输血次数的增加，两组FNHTR发生率随之增高。结论：应用白细胞过滤器对临床输注用全血进行过滤可减少白细胞的输入，从而降低FNHTR的发生率，提高输血的安全性。
목적：관찰응용백세포과려기려제백세포수혈감소발열성비용혈성수혈반응(FNHTR)적림상효과。방법：선택234례환자，안시간단화수혈방식적불동장기분위과려조화대조조。2013년1월지2014년7월채용백세포과려기수혈적168례환자위과려조；2011년5월지2012년12월채용보통일차성수혈기직접수혈적166례환자위대조조。관찰비교량조환자FNHTR적발생솔。결과：①과려조수혈후체온평균승고(0.46±0.67)℃，대조조수혈후체온평균승고(1.38±0.79)℃，대조조체온승고치명현고우과려조，량조차이비교유통계학의의(P＜0.05)；②과려조발생FNHTR 20례，발생솔위11.11%，대조조발생FNHTR42례，발생솔위27.81%,량조FNHTR발생솔상비교，기차이유통계학의의(x2=14.90，P＜0.01)。수착수혈차수적증가，량조FNHTR발생솔수지증고。결론：응용백세포과려기대림상수주용전혈진행과려가감소백세포적수입，종이강저FNHTR적발생솔，제고수혈적안전성。
Objective: To observe the clinical effect of reducing FNHTR by Leucocyte filter dislodging WBC. Methods: One hundred and sixty-eight cases of patients with blood transfusion using leukocyte filter were chosen as filter group in Xianghe County People's Hospital from January 2013 to July 2014,166 cases of patients with blood transfusion using ordinary disposable apparatus as control group from May 2011 to December 2012. The incidences of FNHTR were observed and compared in two groups. The dates were analysed by using SPSS16.0 statistical software. Results:1)Average temperature rise after blood transfusion was (0.46+0.67)℃ in filter group, and was (1.38+0.79)℃ in control group, the difference was statistically significant (P<0.05). 2)The incidence of FNHTR was 11.11% (20/168) in filter group, and was 27.81%(48/166)in control group, the difference was statistically significant (x2=14.90, P<0.01). With the increase of number of blood transfusions, the incidence of FNHTR increased subsequently in two groups. Conclusion: Blood transfusion filtered out white blood cells by using leucocyte filter could reduce the input of white blood cells, so as to reduce the incidence of FNHTR, improve the safety of blood transfusion.