CAJ | 학술논문

目的探讨吲哚菁绿引导的荧光法联合染色法进行早期乳腺癌前哨淋巴结活检的临床应用价值.方法 40例早期乳腺癌患者通过荧光法联合染色法进行前哨淋巴结活检,全部前哨淋巴结均进行术中冰冻及术后石蜡切片病理检查.结果 40例患者均成功行前哨淋巴结活检,其中前哨淋巴结荧光显影率为100％,平均每例2.88枚;蓝染率为92.5％,平均每例1.75枚.7例患者术中冰冻检查发现前哨淋巴结转移癌并立即行腋窝淋巴结清扫.其余33例患者前哨淋巴结术中冰冻病理检查及术后石蜡切片病理检查均未发现转移癌.结论染色法联合荧光法前哨淋巴结活检具备检出率高、创伤小等优势,适宜在临床推广.
목적 탐토신타정록인도적형광법연합염색법진행조기유선암전초림파결활검적림상응용개치.방법 40례조기유선암환자통과형광법연합염색법진행전초림파결활검,전부전초림파결균진행술중빙동급술후석사절편병리검사.결과 40례환자균성공행전초림파결활검,기중전초림파결형광현영솔위100％,평균매례2.88매;람염솔위92.5％,평균매례1.75매.7례환자술중빙동검사발현전초림파결전이암병립즉행액와림파결청소.기여33례환자전초림파결술중빙동병리검사급술후석사절편병리검사균미발현전이암.결론 염색법연합형광법전초림파결활검구비검출솔고、창상소등우세,괄의재림상추엄.
Objective To explore the clinical value of indocyanine green near-infrared fluorescence imaging with methylene blue for the sentinel lymph node biopsy (SLNB) in early breast cancer.Methods SLNB was performed in forty patients by fluorescence navigation with methylene blue.Frozen section was performed,followed by conventional histopathology.Results The identification rate of SLN was 100％.100％ of SLNs were fluorescent,with the average number being 2.88.92.5％ of SLNs were stained blue,with the average number being 1.75.The presence of lymph node metastasis was observed in intraoperative biopsy in 7 patients,and a total dissection of the axillary lymph nodes was performed immediately.Metastatic lesions were not found in the identified lymph nodes by intraoperative biopsy and permanent pathological diagnosis in the other 33 patients.Conclusions Sentinel lymph nodes biopsy by fluorescence navigation with methylene blue was a feasible minimally invasive technology with high detection rate.