中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2015年
3期
148-151
,共4页
顾绍峰%崔长霞%樊兆珊%王利华%陶祥臣%张泳%牟国营
顧紹峰%崔長霞%樊兆珊%王利華%陶祥臣%張泳%牟國營
고소봉%최장하%번조산%왕리화%도상신%장영%모국영
角膜胶原交联术%圆锥角膜%核黄素,低渗%治疗结果
角膜膠原交聯術%圓錐角膜%覈黃素,低滲%治療結果
각막효원교련술%원추각막%핵황소,저삼%치료결과
Corneal collagen cross-linking%Keratoconus%Riboflavin,hypo-osmolar%Therapy outcome
目的 评价低渗核黄素角膜胶原交联术治疗角膜较薄(角膜基质厚度＜400 μm)的圆锥角膜的临床疗效.方法 回顾性病例研究.选取圆锥角膜患者8例(8眼).所有患眼刮除角膜上皮后,行低渗核黄素角膜胶原交联治疗,观察治疗前,治疗后6、12个月,患者的矫正视力、屈光状态、最薄处角膜厚度及角膜内皮细胞密度的变化.结果 治疗前患者最薄处角膜的厚度为418.0 μm,刮除角膜上皮后为383.5 μm,交联治疗后12个月为414.0 μm.治疗前角膜顶点的最大K值、BCVA、角膜内皮细胞密度分别为58.2 D、0.52(logMAR)和2 698.5 cells/mm2,治疗后12个月,上述数据分别为58.9 D、0.46和2 685.9 ceHs/mm2.结论 低渗核黄素角膜胶原交联术是治疗角膜厚度＜400μm的圆锥角膜有效、安全的方式之一.
目的 評價低滲覈黃素角膜膠原交聯術治療角膜較薄(角膜基質厚度＜400 μm)的圓錐角膜的臨床療效.方法 迴顧性病例研究.選取圓錐角膜患者8例(8眼).所有患眼颳除角膜上皮後,行低滲覈黃素角膜膠原交聯治療,觀察治療前,治療後6、12箇月,患者的矯正視力、屈光狀態、最薄處角膜厚度及角膜內皮細胞密度的變化.結果 治療前患者最薄處角膜的厚度為418.0 μm,颳除角膜上皮後為383.5 μm,交聯治療後12箇月為414.0 μm.治療前角膜頂點的最大K值、BCVA、角膜內皮細胞密度分彆為58.2 D、0.52(logMAR)和2 698.5 cells/mm2,治療後12箇月,上述數據分彆為58.9 D、0.46和2 685.9 ceHs/mm2.結論 低滲覈黃素角膜膠原交聯術是治療角膜厚度＜400μm的圓錐角膜有效、安全的方式之一.
목적 평개저삼핵황소각막효원교련술치료각막교박(각막기질후도＜400 μm)적원추각막적림상료효.방법 회고성병례연구.선취원추각막환자8례(8안).소유환안괄제각막상피후,행저삼핵황소각막효원교련치료,관찰치료전,치료후6、12개월,환자적교정시력、굴광상태、최박처각막후도급각막내피세포밀도적변화.결과 치료전환자최박처각막적후도위418.0 μm,괄제각막상피후위383.5 μm,교련치료후12개월위414.0 μm.치료전각막정점적최대K치、BCVA、각막내피세포밀도분별위58.2 D、0.52(logMAR)화2 698.5 cells/mm2,치료후12개월,상술수거분별위58.9 D、0.46화2 685.9 ceHs/mm2.결론 저삼핵황소각막효원교련술시치료각막후도＜400μm적원추각막유효、안전적방식지일.
Objective To evaluate the efficacy of corneal collagen cross-linking (CXL) with a hypo-osmolar riboflavin in keratoconic corneas (corneal thickness less than 400 μm).Methods This retrospective study collected a total of eight eyes of eight keratoconic patients.All patients underwent CXL used a hypo-osmolar riboflavin solution after epithelial removal.The best corrected visual acuity (BCVA),manifest refraction,the thinnest corneal thickness (TCT),and the endothelial cell density (ECD) were evaluated at before and 6,12 months after CXL.Results The TCT was 418.0 μm before treatment and reduced to 383.5 μm after the removal of the epithelium.After CXL,the thickness decreased to 414.0 μm at the last follow up.Before treatment,the K-value of the apex of the keratoconus corneas was 58.2 D,and was 58.9 D at 12-month.The BCVA was 0.52 logarithm of the minimal angle of resolution before treatment,and increased to 0.46 logarithm at the last follow up.The ECD was 2 698.5 cells/mm2 before treatment,and was 2 685.9 cells/mm2 at 12-month after treatment.Conclusion CXL with a hypo-osmolar riboflavin is one of safe and effective treatment in keratoconic eyes with thin corneas (corneal thickness less than 400 μm).
