中华眼视光学与视觉科学杂志
中華眼視光學與視覺科學雜誌
중화안시광학여시각과학잡지
CHINESE JOURNAL OF OPTOMETRY OPHTHALMOLOGY AND VISUAL SCIENCE
2015年
3期
181-183
,共3页
羟氯喹%体层摄影术,光学相干%视网膜厚度%视网膜毒性
羥氯喹%體層攝影術,光學相榦%視網膜厚度%視網膜毒性
간록규%체층섭영술,광학상간%시망막후도%시망막독성
Hydroxychloroquine%Tomography optical coherence%Retinal thickness
目的 通过OCT评估羟氯喹对视网膜神经纤维层(RNFL)的损害.方法 回顾性病例研究.对30例使用羟氯喹治疗少于5年并且没有发生眼底改变的患者和30例健康者进行视力、视野、眼底和OCT的检查.结果 治疗期间视力、眼底和视野的检查均无异常.OCT发现服用羟氯喹组患者的内层黄斑区视网膜厚度内外圈各象限均有显著降低.结论 OCT能观察到羟氯喹对视网膜的早期损伤.
目的 通過OCT評估羥氯喹對視網膜神經纖維層(RNFL)的損害.方法 迴顧性病例研究.對30例使用羥氯喹治療少于5年併且沒有髮生眼底改變的患者和30例健康者進行視力、視野、眼底和OCT的檢查.結果 治療期間視力、眼底和視野的檢查均無異常.OCT髮現服用羥氯喹組患者的內層黃斑區視網膜厚度內外圈各象限均有顯著降低.結論 OCT能觀察到羥氯喹對視網膜的早期損傷.
목적 통과OCT평고간록규대시망막신경섬유층(RNFL)적손해.방법 회고성병례연구.대30례사용간록규치료소우5년병차몰유발생안저개변적환자화30례건강자진행시력、시야、안저화OCT적검사.결과 치료기간시력、안저화시야적검사균무이상.OCT발현복용간록규조환자적내층황반구시망막후도내외권각상한균유현저강저.결론 OCT능관찰도간록규대시망막적조기손상.
Objective To evaluate the damage to retinal function in patients receiving hydroxychloroquine (HCQ) by observing the changes in the retinal nerve fiber layer (RNFL).Methods A retrospective study was performed on 30 patients with rheumatoid arthritis who were treated with HCQ therapy and 30 healthy people.Visual acuity,visual field and fundus examinations as well as optical coherence tomography (OCT) were compared between the two groups.Results Visual acuity,visual field and fundus examinations were normal.Decreases were noted with OCT.Conclusion OCT can detect early retinal toxicity due to hydroxychloroquine.
