CAJ | 학술논문

目的采用核磁共振法确定健康志愿者液体胃排空时间,为探讨合理的术前禁饮时间提供参考.方法选择健康志愿者19名,ASA分级Ⅰ或Ⅱ级,年龄20～ 60岁,性别不限.于试验前1 d 22:00时开始禁饮、禁食,试验当日8:00(T0)时进行MRI检查,记录基础胃内液体容积.口服12.5％碳水化合物溶液(含40 g麦芽糊精和10 g蔗糖)400 ml.于口服溶液后即刻测量胃内液体容积,之后每25 min复测1次,直至胃内液体容积恢复至口服前基础状态或者小于25 ml,分别记录为T25、T50、T75、T100等.将液体容积通过计算机作图,得到胃排空曲线,计算半量胃排空时间和完全胃排空时间.结果志愿者液体半量胃排空时间(32±12) min,完全胃排空时间(99±22) min.与T0时比较,T25 、T50、T75 、T100时胃内液体容积增多(P＜0.05),T125、T150和T175时胃内液体容积差异无统计学意义(P＞0.05).结论健康志愿者液体胃排空时间约为2h,提示禁饮时间可缩短至麻醉前2h.
목적 채용핵자공진법학정건강지원자액체위배공시간,위탐토합리적술전금음시간제공삼고.방법 선택건강지원자19명,ASA분급Ⅰ혹Ⅱ급,년령20～ 60세,성별불한.우시험전1 d 22:00시개시금음、금식,시험당일8:00(T0)시진행MRI검사,기록기출위내액체용적.구복12.5％탄수화합물용액(함40 g맥아호정화10 g자당)400 ml.우구복용액후즉각측량위내액체용적,지후매25 min복측1차,직지위내액체용적회복지구복전기출상태혹자소우25 ml,분별기록위T25、T50、T75、T100등.장액체용적통과계산궤작도,득도위배공곡선,계산반량위배공시간화완전위배공시간.결과 지원자액체반량위배공시간(32±12) min,완전위배공시간(99±22) min.여T0시비교,T25 、T50、T75 、T100시위내액체용적증다(P＜0.05),T125、T150화T175시위내액체용적차이무통계학의의(P＞0.05).결론 건강지원자액체위배공시간약위2h,제시금음시간가축단지마취전2h.
Objective To determine the gastric emptying time for liquids in the healthy volunteers by magnetic resonance imaging (MRI) and to provide a reference for reasonable preoperative fasting time.Methods Nineteen healthy volunteers of both sexes,of ASA physical status Ⅰ or Ⅱ,aged 20-60 yr,were enrolled in the study.The volunteers were fasted from the intake of liquids or solids starting from 22:00 the night before the trial,and 12.5％ carbohydrate solution 400 ml containing 40 g maltodextrin and 10 g sucrose was given orally.MRI was performed to measure the baseline gastric fluid volume at 8:00 on the day of the trial (T0).The gastric fluid volume was measured immediately after administration of the oral solution,and then measured every 25 min until the gastric fluid volume was returned to the baseline before administration of the oral solution or to ＜25 ml,and was recorded as T25,T50,T75,T100,et al.The gastric fluid volume was drawn using a computer to obtain the curve for gastric emptying.The gastric half and total emptying time was calculated using the curves.Results The gastric half emptying time was (32± 12) min,and the gastric total emptying time was (99±22) min in the volunteers.Compared with those at Tb,the gastric fluid volume was significantly increased at T25,T50,T75,T100,and no significant change was found in gastric fluid volume at T125,T150and T175.Conclusion After oral intake of liquids,the gastric emptying time is about 2 h,indicating that the preoperative fasting time for liquids can be shortened to 2 h before anesthesia in the healthy volunteers.