吉林医学
吉林醫學
길림의학
JILIN MEDICAL JOURANL
2015年
10期
1949-1950
,共2页
阿昔洛韦%传染性单核细胞增多症%临床效果
阿昔洛韋%傳染性單覈細胞增多癥%臨床效果
아석락위%전염성단핵세포증다증%림상효과
Acyclovir%Infectious mononucleosis syndrome%Clinical effect
目的：评价阿昔洛韦治疗传染性单核细胞增多症的临床效果。方法：根据纳入/排除标准共选取83例病例作为本次研究对象并随机分组；对照组给予常规对症处理，研究组给予常规对症处理加阿昔洛韦治疗；比较两组患儿体温恢复正常、淋巴结肿大消失、咽峡炎症状消失、异型淋巴细胞〈10％及住院时间及治疗期内不良反应发生情况。结果：研究组患儿体温恢复正常、淋巴结肿大消失、咽峡炎症状消失、异型淋巴细胞〈10％及住院时间值依次为（4.1±1.3）d（、6.7±2.8）d（、6.8 ± 2.0）d（、8.4±4.5）d、（9.2±2.6）d，均较对照组明显缩短，差异有统计学意义（P〈0.05）；两组治疗期内均未发生明显不良反应，均按预定计划完成治疗。结论：阿昔洛韦治疗传染性单核细胞增多症的临床效果较佳，可有效缓解患儿发热、淋巴结肿大、咽峡炎等临床症状，促进患儿早期恢复，避免发生严重并发症，值得临床推广应用。
目的：評價阿昔洛韋治療傳染性單覈細胞增多癥的臨床效果。方法：根據納入/排除標準共選取83例病例作為本次研究對象併隨機分組；對照組給予常規對癥處理，研究組給予常規對癥處理加阿昔洛韋治療；比較兩組患兒體溫恢複正常、淋巴結腫大消失、嚥峽炎癥狀消失、異型淋巴細胞〈10％及住院時間及治療期內不良反應髮生情況。結果：研究組患兒體溫恢複正常、淋巴結腫大消失、嚥峽炎癥狀消失、異型淋巴細胞〈10％及住院時間值依次為（4.1±1.3）d（、6.7±2.8）d（、6.8 ± 2.0）d（、8.4±4.5）d、（9.2±2.6）d，均較對照組明顯縮短，差異有統計學意義（P〈0.05）；兩組治療期內均未髮生明顯不良反應，均按預定計劃完成治療。結論：阿昔洛韋治療傳染性單覈細胞增多癥的臨床效果較佳，可有效緩解患兒髮熱、淋巴結腫大、嚥峽炎等臨床癥狀，促進患兒早期恢複，避免髮生嚴重併髮癥，值得臨床推廣應用。
목적：평개아석락위치료전염성단핵세포증다증적림상효과。방법：근거납입/배제표준공선취83례병례작위본차연구대상병수궤분조；대조조급여상규대증처리，연구조급여상규대증처리가아석락위치료；비교량조환인체온회복정상、림파결종대소실、인협염증상소실、이형림파세포〈10％급주원시간급치료기내불량반응발생정황。결과：연구조환인체온회복정상、림파결종대소실、인협염증상소실、이형림파세포〈10％급주원시간치의차위（4.1±1.3）d（、6.7±2.8）d（、6.8 ± 2.0）d（、8.4±4.5）d、（9.2±2.6）d，균교대조조명현축단，차이유통계학의의（P〈0.05）；량조치료기내균미발생명현불량반응，균안예정계화완성치료。결론：아석락위치료전염성단핵세포증다증적림상효과교가，가유효완해환인발열、림파결종대、인협염등림상증상，촉진환인조기회복，피면발생엄중병발증，치득림상추엄응용。
Objective To evaluate the clinical effect of acyclovir in the treatment of infectious mononucleosis. Method According to the inclusion / exclusion criteria 83 cases were selected as the research object and randomly divided into two groups;the control group was given routine symptomatic treatment plus ribavirin therapy,the study group was given conventional treatment and acyclovir treatment the temperature returned to normal,lymphadenopathy disappeared,angina symptoms,atypical lymphocytes ﹤ 10% and in hospital time and treatment period and adverse reaction in two groups were compared. Results The study group with the temperature returned to normal,lymphadenopathy disap-peared,angina symptoms,atypical lymphocytes ﹤ 10% and hospitalization time values were(4. 1 ± 1. 3)d(,6. 7 ± 2. 8)d(,6. 8 ± 2. 0) d(,8. 4 ± 4. 5)d(,9. 2 ± 2. 6)d,mean significantly shorter than the control group,there was significant difference( P﹤0. 05);treatment in the two groups were no obvious adverse reactions,completed the treatment according to schedule. Conclusion The clinical effect of acyclov-ir in the treatment of infectious mononucleosis syndrome is better,can effectively alleviate children,fever,swollen lymph nodes,go far angina symptoms,promote early recovery of children,to avoid serious complications. It is worthy of clinical application.
