CAJ | 학술논문

拉曼光谱是根据拉曼散射原理而形成的一项光谱技术，被广泛地应用于医学和生命科学的研究中。拉曼光谱可以检测生物样本中蛋白质、脂质、DNA和其他生物大分子的结构和组成，提供丰富的分子水平信息，被称为“分子指纹”。拉曼光谱可以早期检测出组织中生物大分子结构、成分和含量的改变，灵敏度高且特异性强，方便快速，在疾病的早期诊断中具有较高的优势，被广泛应用于医学研究领域。目前，拉曼光谱技术已经成为临床原位诊断技术的研究热点，在口腔医学领域的应用愈发普及。本文通过复习文献，对拉曼光谱在口腔医学中的应用作一综述。
랍만광보시근거랍만산사원리이형성적일항광보기술，피엄범지응용우의학화생명과학적연구중。랍만광보가이검측생물양본중단백질、지질、DNA화기타생물대분자적결구화조성，제공봉부적분자수평신식，피칭위“분자지문”。랍만광보가이조기검측출조직중생물대분자결구、성분화함량적개변，령민도고차특이성강，방편쾌속，재질병적조기진단중구유교고적우세，피엄범응용우의학연구영역。목전，랍만광보기술이경성위림상원위진단기술적연구열점，재구강의학영역적응용유발보급。본문통과복습문헌，대랍만광보재구강의학중적응용작일종술。
Raman?spectroscopy?is?an?optical?technology?based?on?the?theory?of?Raman?scattering,?which?is?generally?used?in?the?research?of?medical?and?biological?science.?Raman?spectroscopy?can?be?used?to?detect?the?molecular?structures?and?com-ponents?of?proteins,?lipids,?DNA,?and?other?biological?molecules,?and?provide?substantial?information?about?molecules.?Thus,?Raman?spectroscopy?is?generally?considered?a?“molecular?fingerprint”,?and?it?has?exceptional?advantages?in?medical?research.?Moreover,?this?technique?can?reflect?the?changes?in?molecular?structures?and?detect?the?alterations?of?chemical?constituents?in?the?samples.?Raman?spectroscopy,?given?its?high?sensitivity?and?specificity?in?the?detection?of?the?biological?samples,?has?been?successfully?used?to?detect?and?diagnose?diseases?in?numerous?sites,?such?as?skin,?oral?mucosa,?breast,?head,?and?neck.?In?this?paper,?we?introduce?the?application?of?Raman?spectroscopy?in?stomatology?by?conducting?a?review?of?the?literature.