中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
4期
604-606
,共3页
舒芬太尼%腹部手术%自控静脉镇痛%地佐辛
舒芬太尼%腹部手術%自控靜脈鎮痛%地佐辛
서분태니%복부수술%자공정맥진통%지좌신
Sufentanil%Abdominal operation%PCIA%Dezocine
目的：研究舒芬太尼联合地佐辛用于腹部手术术后自控静脉镇痛（ PCIA）的效果。方法：110例接受腹部手术患者随机分为观察组和对照组各55例，术后均予电子镇痛泵进行PCIA。对照组给予地佐辛0.3 mg·kg-1，观察组给予舒芬太尼注射液0.1μg·kg-1+地佐辛0.3 mg·kg-1。比较两组患者VAS评分、药品不良反应、Ramesay评分、自控镇痛按压次数、排气时间、肠鸣音恢复时间、肠鸣音频率等指标，观察两组患者术后PCIA效果。结果：观察组的术后6~24 h VAS评分、Rames-ay评分，12~24 h的自控镇痛按压次数等指标均明显优于对照组（ P<0.01），排气时间、肠鸣音恢复时间、肠鸣音频率等也明显好于对照组（ P<0.01）。观察组药品不良反应发生率明显高于对照组（ P<0.05或0.01）。结论：舒芬太尼联合地佐辛用于腹部手术术后的PCIA，镇痛、镇静效果显著，能明显改善患者临床症状，值得临推广应用。
目的：研究舒芬太尼聯閤地佐辛用于腹部手術術後自控靜脈鎮痛（ PCIA）的效果。方法：110例接受腹部手術患者隨機分為觀察組和對照組各55例，術後均予電子鎮痛泵進行PCIA。對照組給予地佐辛0.3 mg·kg-1，觀察組給予舒芬太尼註射液0.1μg·kg-1+地佐辛0.3 mg·kg-1。比較兩組患者VAS評分、藥品不良反應、Ramesay評分、自控鎮痛按壓次數、排氣時間、腸鳴音恢複時間、腸鳴音頻率等指標，觀察兩組患者術後PCIA效果。結果：觀察組的術後6~24 h VAS評分、Rames-ay評分，12~24 h的自控鎮痛按壓次數等指標均明顯優于對照組（ P<0.01），排氣時間、腸鳴音恢複時間、腸鳴音頻率等也明顯好于對照組（ P<0.01）。觀察組藥品不良反應髮生率明顯高于對照組（ P<0.05或0.01）。結論：舒芬太尼聯閤地佐辛用于腹部手術術後的PCIA，鎮痛、鎮靜效果顯著，能明顯改善患者臨床癥狀，值得臨推廣應用。
목적：연구서분태니연합지좌신용우복부수술술후자공정맥진통（ PCIA）적효과。방법：110례접수복부수술환자수궤분위관찰조화대조조각55례，술후균여전자진통빙진행PCIA。대조조급여지좌신0.3 mg·kg-1，관찰조급여서분태니주사액0.1μg·kg-1+지좌신0.3 mg·kg-1。비교량조환자VAS평분、약품불량반응、Ramesay평분、자공진통안압차수、배기시간、장명음회복시간、장명음빈솔등지표，관찰량조환자술후PCIA효과。결과：관찰조적술후6~24 h VAS평분、Rames-ay평분，12~24 h적자공진통안압차수등지표균명현우우대조조（ P<0.01），배기시간、장명음회복시간、장명음빈솔등야명현호우대조조（ P<0.01）。관찰조약품불량반응발생솔명현고우대조조（ P<0.05혹0.01）。결론：서분태니연합지좌신용우복부수술술후적PCIA，진통、진정효과현저，능명현개선환자림상증상，치득림추엄응용。
Objective:To study the effect of sufentanil combined with dezocine on the PCIA after abdominal operation. Methods:Totally 110 patients undergoing abdominal operation were randomly divided into the experimental group and the control group with 55 cases in each. The two groups were both treated with electronic analgesia pump for the PCIA after the operation. The control group was given dezocine 0. 3 mg·kg-1 ,and the experimental group was given sufentanil injections 0. 1 g·kg-1 plus dezocine 0. 3 mg·kg-1 . The VAS score,adverse drug reactions,Ramesay scores,press number of patient controlled analgesia,exhaust time,recovery time of bowel sounds and bowel audio rate index in the two groups were compared to evaluate the effect of PCIA. Results:All the observed in-dices in the experimental group were significantly better than those in the control group(P<0. 01). The incidence of adverse reactions in the experimental group was significantly higher than that in the control group(P<0. 01). Conclusion:Sufentanil combined with dezocine for the PCIA after abdominal operation shows significantly analgesic and sedative effects,and can notably improve the clinical symptoms,which is worthy of clinical application.
