中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
4期
621-623
,共3页
冠心病心绞痛%丹红注射液%疗效%安全性
冠心病心絞痛%丹紅註射液%療效%安全性
관심병심교통%단홍주사액%료효%안전성
Angina pectoris%Danhong injections%Efficacy%Safety
目的：探讨冠心病心绞痛采用丹红注射液治疗的临床疗效及安全性。方法：120例冠心病心绞痛患者随机均分为观察组和对照组。对照组患者给予吸氧、抗感染、祛痰及平喘等常规治疗，观察组在对照组基础上加用丹红注射液30 ml+5%葡萄糖注射液250 ml，ivd，qd。两组疗程均为2周。比较两组治疗前后的血液流变学及血脂变化情况，评价两组治疗后的心电图和临床症状改善的疗效。结果：治疗后，两组患者的血液流变学指标均较前明显降低（ P<0.01），且观察组患者改善效果明显优于对照组（P<0.01）。两组患者的TC、TG、LDL均较前明显降低（P<0.01），HDL较前明显升高（P<0.01），且观察组各项指标较治疗前的改善效果明显优于对照组（ P<0.01）。观察组临床症状改善与心电图改善总有效率均明显高于对照组（P<0.05）。结论：丹红注射液治疗冠心病心绞痛，可显著改善患者的血液流变学和血脂状况，提高治疗的临床疗效，值得广泛推广应用。
目的：探討冠心病心絞痛採用丹紅註射液治療的臨床療效及安全性。方法：120例冠心病心絞痛患者隨機均分為觀察組和對照組。對照組患者給予吸氧、抗感染、祛痰及平喘等常規治療，觀察組在對照組基礎上加用丹紅註射液30 ml+5%葡萄糖註射液250 ml，ivd，qd。兩組療程均為2週。比較兩組治療前後的血液流變學及血脂變化情況，評價兩組治療後的心電圖和臨床癥狀改善的療效。結果：治療後，兩組患者的血液流變學指標均較前明顯降低（ P<0.01），且觀察組患者改善效果明顯優于對照組（P<0.01）。兩組患者的TC、TG、LDL均較前明顯降低（P<0.01），HDL較前明顯升高（P<0.01），且觀察組各項指標較治療前的改善效果明顯優于對照組（ P<0.01）。觀察組臨床癥狀改善與心電圖改善總有效率均明顯高于對照組（P<0.05）。結論：丹紅註射液治療冠心病心絞痛，可顯著改善患者的血液流變學和血脂狀況，提高治療的臨床療效，值得廣汎推廣應用。
목적：탐토관심병심교통채용단홍주사액치료적림상료효급안전성。방법：120례관심병심교통환자수궤균분위관찰조화대조조。대조조환자급여흡양、항감염、거담급평천등상규치료，관찰조재대조조기출상가용단홍주사액30 ml+5%포도당주사액250 ml，ivd，qd。량조료정균위2주。비교량조치료전후적혈액류변학급혈지변화정황，평개량조치료후적심전도화림상증상개선적료효。결과：치료후，량조환자적혈액류변학지표균교전명현강저（ P<0.01），차관찰조환자개선효과명현우우대조조（P<0.01）。량조환자적TC、TG、LDL균교전명현강저（P<0.01），HDL교전명현승고（P<0.01），차관찰조각항지표교치료전적개선효과명현우우대조조（ P<0.01）。관찰조림상증상개선여심전도개선총유효솔균명현고우대조조（P<0.05）。결론：단홍주사액치료관심병심교통，가현저개선환자적혈액류변학화혈지상황，제고치료적림상료효，치득엄범추엄응용。
Objective:To evaluate the clinical efficacy and safety of Danhong injections in the adjuvant therapy for angina pecto-ris. Methods:According to a random number table,totally 120 cases of patients with angina pectoris were randomly divided into the observation group and the control group. The control group was treated with the conventional therapy,such as oxygen uptake,anti-in-flammation,expectoration and relieving asthma,and the observation group was treated with Danhong injections(30ml added in 250ml glucose infusions,ivd,qd)additionally. The treatment course was 2 weeks. The hemorheology and blood lipid changes before and af-ter the treatment were recorded,the ECG was analyzed and the clinical symptom improvement was evaluated in the two groups. Re-sults:After the treatment,the hemorheological indices of the two groups were significantly reduced(P<0. 01),and the improvement of the observation group was much better than that of the control group(P<0. 01). After the treatment,the TC,TG and LDL were significantly lower and the HDL was notably higher than those before the treatment in the two groups(P<0. 01),and the improvement of the observation group was significantly better than that in the control group(P<0. 01). The total efficiency of ECG and clinical symptom improvement in the observation group was significantly higher than that in the control group(P<0. 05). Conclusion:Dan-hong injections in the treatment of angina pectoris can significantly improve the hemorheology and blood lipid to enhance the clinical ef-ficacy,which are worthy of promoted application.
