CAJ | 학술논문

目的：根据《抗菌药物临床应用指导原则》加强管理后，探讨骨科围手术期抗菌药物使用情况。方法：对2011年3月~2011年12月骨科无菌手术患者793例，2012年3月~2011年12月骨科无菌手术患者857例，预防性使用抗菌药物进行比较评价。结果：2011、2012年组围手术期抗菌药物使用率为100％、52.6％，使用时间为（8.61±4.47）d、（2.11±1.34）d，两组差异有统计学意义（P﹤0.05）。2011组切口感染率为0.56％，2012组切口感染率为0.42％。结论：强化管理后，短时间、规范、合理使用抗菌药物安全、有效，能显著减少围手术期抗菌药物的使用率，不增加切口感染的发生率。
목적：근거《항균약물림상응용지도원칙》가강관리후，탐토골과위수술기항균약물사용정황。방법：대2011년3월~2011년12월골과무균수술환자793례，2012년3월~2011년12월골과무균수술환자857례，예방성사용항균약물진행비교평개。결과：2011、2012년조위수술기항균약물사용솔위100％、52.6％，사용시간위（8.61±4.47）d、（2.11±1.34）d，량조차이유통계학의의（P﹤0.05）。2011조절구감염솔위0.56％，2012조절구감염솔위0.42％。결론：강화관리후，단시간、규범、합리사용항균약물안전、유효，능현저감소위수술기항균약물적사용솔，불증가절구감염적발생솔。
Objective To discussion the clinical application of antibiotics in the peroperative period after guided by“Guiding Principles of Clinical application of antibacterial drug”. Method The data of 793 Aseptic operation patients in department of Orthopedics from March to December 2011 and 857 Aseptic operation patients from March to December 2012 were selected retrospectively to compare and review the anti-biotics utilization the situation of perioperative period. Results The percentage of antibiotics use in 2011 group and 2012 group were 100%and 52. 6% retrospectively(P﹤0. 05). The use of time were(8. 61 ± 4. 47)d and(2. 11 ± 1. 34)d in two group retrospectively,the differ-ence was statistically significant( P﹤0. 05). The rate of incision infection were 0. 56% and 0. 42% retrospectively. Conclusion The study shows that the method of short time,norms and rational use of antibiotics is safe and effective after strengthening antibiotics management, which can significantly reduce antibiotic use and does not increase the occurrence of incision infection.