CAJ | 학술논문

目的：研究贞冰口溃宁含片抗炎镇痛促进溃疡愈合的作用。方法：采用巴豆油致小鼠耳廓肿胀法观察其抗炎作用，醋酸致小鼠扭体法观察其镇痛作用，醋酸致金黄地鼠口腔溃疡法观察其促进溃疡愈合的作用。结果：贞冰口溃宁含片能明显减轻小鼠耳廓肿胀度（P<0.01）；减少小鼠扭体次数（P<0.05）；显著缩小溃疡直径（P<0.01或P<0.05），减轻炎症反应。结论：贞冰口溃宁含片具有抗炎、镇痛、促进溃疡愈合的作用。
목적：연구정빙구궤저함편항염진통촉진궤양유합적작용。방법：채용파두유치소서이곽종창법관찰기항염작용，작산치소서뉴체법관찰기진통작용，작산치금황지서구강궤양법관찰기촉진궤양유합적작용。결과：정빙구궤저함편능명현감경소서이곽종창도（P<0.01）；감소소서뉴체차수（P<0.05）；현저축소궤양직경（P<0.01혹P<0.05），감경염증반응。결론：정빙구궤저함편구유항염、진통、촉진궤양유합적작용。
Objective:To investigate the anti-inflammation,analgesia and ulcer healing promotion of Zhenbing Koukuining tab-lets. Methods:The anti-inflammatin,analgesia and ulcer healing promotion of the preparation was respectively observed in the croton oil-induced auricular edema in mice,acetic acid-induced writhing in mice and acetic acid-induced oral ulcer in golden hamsters. Re-sults:The tablets could obviously alleviate the auricular edema(P<0. 01)and reduce the writhing times in mice(P<0. 05),and nar-row the oral ulcer(P<0. 01 or P<0. 05)and inhibit the inflammation reaction in golden hamsters. Conclusion:Zhenbing Koukuining tablets have anti-inflammatory,analgesia and ulcer healing promotion effects.