吉林医学
吉林醫學
길림의학
JILIN MEDICAL JOURANL
2015年
10期
1992-1993
,共2页
小儿门诊手术%全身麻醉%苏醒期躁动%预防方法
小兒門診手術%全身痳醉%囌醒期躁動%預防方法
소인문진수술%전신마취%소성기조동%예방방법
Pediatric outpatient operation%General anesthesia%Emergence agitation(EA)%Preventive method
目的：探讨咪达唑仑、曲马多、舒芬太尼三种药物预防小儿门诊短小手术全身麻醉苏醒期躁动的效果。方法：小儿外科门诊手术800例，随机分4组，全部采用氯胺酮-丙泊酚静脉复合全身麻醉。A 组：术毕时不给任何预防性用药，作为对照组；B 组：静脉滴注咪达唑仑0.1 mg/ kg；C 组：静脉滴注曲马多1 mg/ kg；D 组：静脉滴注舒芬太尼0.5μg/ kg。统计苏醒期轻、中、重躁动例数和总发生率。结果：A 组患者躁动发生率高，躁动重度占55.2％；B、C 组患者轻、中、重度躁动发生率、总发生率均低于 A组（P ﹤0.01）；D 组重度躁动发生率和总发生率明显低于前三组，差异有统计学意义（P ﹤0.01）。结论：咪达唑仑、曲马多、舒芬太尼三种药物能明显降低小儿门诊短小手术全身麻醉苏醒期躁动发生率，其中舒芬太尼组最低，强效镇痛药物预防效果最为显著。
目的：探討咪達唑崙、麯馬多、舒芬太尼三種藥物預防小兒門診短小手術全身痳醉囌醒期躁動的效果。方法：小兒外科門診手術800例，隨機分4組，全部採用氯胺酮-丙泊酚靜脈複閤全身痳醉。A 組：術畢時不給任何預防性用藥，作為對照組；B 組：靜脈滴註咪達唑崙0.1 mg/ kg；C 組：靜脈滴註麯馬多1 mg/ kg；D 組：靜脈滴註舒芬太尼0.5μg/ kg。統計囌醒期輕、中、重躁動例數和總髮生率。結果：A 組患者躁動髮生率高，躁動重度佔55.2％；B、C 組患者輕、中、重度躁動髮生率、總髮生率均低于 A組（P ﹤0.01）；D 組重度躁動髮生率和總髮生率明顯低于前三組，差異有統計學意義（P ﹤0.01）。結論：咪達唑崙、麯馬多、舒芬太尼三種藥物能明顯降低小兒門診短小手術全身痳醉囌醒期躁動髮生率，其中舒芬太尼組最低，彊效鎮痛藥物預防效果最為顯著。
목적：탐토미체서륜、곡마다、서분태니삼충약물예방소인문진단소수술전신마취소성기조동적효과。방법：소인외과문진수술800례，수궤분4조，전부채용록알동-병박분정맥복합전신마취。A 조：술필시불급임하예방성용약，작위대조조；B 조：정맥적주미체서륜0.1 mg/ kg；C 조：정맥적주곡마다1 mg/ kg；D 조：정맥적주서분태니0.5μg/ kg。통계소성기경、중、중조동례수화총발생솔。결과：A 조환자조동발생솔고，조동중도점55.2％；B、C 조환자경、중、중도조동발생솔、총발생솔균저우 A조（P ﹤0.01）；D 조중도조동발생솔화총발생솔명현저우전삼조，차이유통계학의의（P ﹤0.01）。결론：미체서륜、곡마다、서분태니삼충약물능명현강저소인문진단소수술전신마취소성기조동발생솔，기중서분태니조최저，강효진통약물예방효과최위현저。
Objective To observe the preventive effects of midazolam,tramadol,sufentanil three kinds drugs on emergence agitation (EA)under general anesthesia in pediatric outpatient short operation. Method 800 cases in pediatric surgery operation were randomly di-vided into 4 groups,all received anesthesia induction with ketamine and propofol. Group A did not give any prophylactic medication at the end of operation,as control group. Group B was intravenously injected with midazolam 0. 1 mg/ kg. Group C was intravenously injected with tramadol 1mg/ kg. Group D was intravenously injected with sufentanil 0. 5 μg/ kg. Light,middle,heavy and total EA incidence rate in recov-ery period were analyzed. Results The EA incidence rate was high in group A,55. 2% of them were heavy EA. Group B,C light,middle, heavy and total EA incidence rate were lower than group A(P ﹤ 0. 01). Group D heavy and total EA incidence rate were obviously lower than the other three groups(P ﹤ 0. 01). Conclusion Midazolam,tramadol,sufentanil can significantly reduce EA incidence rate under gen-eral anesthesia in pediatric outpatient short operation,which sufentanil group is the lowest,show preventive effect of potent analgesic is the most significant.
