CAJ | 학술논문

目的：观察益肾化瘀汤对糖尿病肾病患者CysC（半胱氨酸蛋白酶抑制剂C）、Hcy（同型半胱氨酸）、hs-CRP（超敏C-反应蛋白）水平的影响。方法：140例随机分为观察组和对照组各70例，两组均实施糖尿病常规治疗，对照组加用厄贝沙坦，观察组加用益气化瘀汤。结果：观察组治疗后hs-CRP、Hcy、CysC水平均显著低于对照组（P＜0.05）。总有效率观察组80.00%，对照组45.71%，两组比较差异有统计学意义（P＜0.05）。结论：益肾化瘀汤治疗糖尿病肾病可有效调节血糖代谢，减少尿蛋白排泄，降低CysC、Hcy及hs-CRP水平，从而延缓病情进展。
목적：관찰익신화어탕대당뇨병신병환자CysC（반광안산단백매억제제C）、Hcy（동형반광안산）、hs-CRP（초민C-반응단백）수평적영향。방법：140례수궤분위관찰조화대조조각70례，량조균실시당뇨병상규치료，대조조가용액패사탄，관찰조가용익기화어탕。결과：관찰조치료후hs-CRP、Hcy、CysC수평균현저저우대조조（P＜0.05）。총유효솔관찰조80.00%，대조조45.71%，량조비교차이유통계학의의（P＜0.05）。결론：익신화어탕치료당뇨병신병가유효조절혈당대사，감소뇨단백배설，강저CysC、Hcy급hs-CRP수평，종이연완병정진전。
Objective:To observe the effect of Yishen Huayu Decoction on the level of CSYC, Hcy and hs-CRP in serum of diabetic nephropathy patients. Method:140 cases were divided into two groups evenly in random. Both groups were treated with conventional therapy for diabetes. The control group were treated with Irbesartan additionally while the study group were treated with Yiqi Huayu Decoction additionally. Result:After the treatment, the level of CSYC, Hcy and hs-CRP of the study group was lower than that of the control group significantly (P<0.05). The total effective rate of the study group was 80.00%while that of the control group was 45.71%. There was statistical significance between the two groups (P<0.05). Conclusion:Yiqi Huayu Decoction could regulate the metabolism of blood glucose, reduce urine albumin excretion and decrease the level of CSYC, Hcy and hs-CRP in treating diabetic nephropathy effectively to retard the progress of disease.