中国药师
中國藥師
중국약사
CHINA PHARMACIST
2015年
4期
649-651,697
,共4页
马冬冬%孟庆丽%刘红梅%吴琳华%唐景玲
馬鼕鼕%孟慶麗%劉紅梅%吳琳華%唐景玲
마동동%맹경려%류홍매%오림화%당경령
阴道黏膜给药%凝胶%阴道膜剂%脂质体%纳米银
陰道黏膜給藥%凝膠%陰道膜劑%脂質體%納米銀
음도점막급약%응효%음도막제%지질체%납미은
Vaginal mucoadhesive drug delivery%Gels%Vaginal films%Liposomes%üano-silver
目的：综述阴道黏膜给药系统的最新应用进展。方法：根据国内外发表的文献，对阴道黏膜给药系统的应用加以分析和讨论。结果：阴道黏膜给药安全、有效、能避免首关效应、渗透性能强，延长药物滞留时间，提高生物利用度，可以改善患者用药顺应性。结论：阴道黏膜给药系统已成为目前研究的热点，它是传统给药方式的补充，具有广阔的应用前景。
目的：綜述陰道黏膜給藥繫統的最新應用進展。方法：根據國內外髮錶的文獻，對陰道黏膜給藥繫統的應用加以分析和討論。結果：陰道黏膜給藥安全、有效、能避免首關效應、滲透性能彊，延長藥物滯留時間，提高生物利用度，可以改善患者用藥順應性。結論：陰道黏膜給藥繫統已成為目前研究的熱點，它是傳統給藥方式的補充，具有廣闊的應用前景。
목적：종술음도점막급약계통적최신응용진전。방법：근거국내외발표적문헌，대음도점막급약계통적응용가이분석화토론。결과：음도점막급약안전、유효、능피면수관효응、삼투성능강，연장약물체류시간，제고생물이용도，가이개선환자용약순응성。결론：음도점막급약계통이성위목전연구적열점，타시전통급약방식적보충，구유엄활적응용전경。
Objective:To review the progress in vaginal mucoadhesive drug delivery systems. Methods:Based on the recently published papers,the research on the application of vaginal mucoadhesive drug delivery systems was classified and summarized. Re-sults:Vaginal mucoadhesive drug delivery systems not only showed safety,effectiveness and strong permeability but also avoided the first pass effect,prolonged drug residence time and improved bioavailability and compliance of patients. Conclusion:Vaginal mucoad-hesive drug delivery systems are becoming research hotspots and exhibit broad application prospects to replace the traditional delivery systems.
