中华放射肿瘤学杂志
中華放射腫瘤學雜誌
중화방사종류학잡지
CHINESE JOURNAL OF RADIATION ONCOLOGY
2015年
2期
184-188
,共5页
彭应林%刘松然%黄伯天%林茂盛%张丹丹%胡江%刘慧%罗广文%邓小武
彭應林%劉鬆然%黃伯天%林茂盛%張丹丹%鬍江%劉慧%囉廣文%鄧小武
팽응림%류송연%황백천%림무성%장단단%호강%류혜%라엄문%산소무
体层摄影术,X线计算机,锥形束%图像配准%相似性指数%肺肿瘤
體層攝影術,X線計算機,錐形束%圖像配準%相似性指數%肺腫瘤
체층섭영술,X선계산궤,추형속%도상배준%상사성지수%폐종류
Tomography,X-ray computed,cone-beam%Image registration%Dice similarity coefficient%Lung neoplasms
目的 比较和评估使用CBCT图像引导摆位中不同图像配准方法对配准精度的影响,为选择合理的图像引导方法提供临床依据.方法 对15例肺癌患者计划CT和第1次放疗摆位CBCT图像分别以不同算法(骨性或灰度配准)和不同范围(靶区或患侧或体廓)进行图像配准,比较各组配准的治疗体位下PTVCT对GTVCBCT的覆盖率、靶区和OAR相似性指数及GTV几何中心位置偏差.结果 相同配准范围骨性配准精度差于灰度配准,其中配准靶区组差别最明显.骨性和灰度配准方式配准靶区、患侧及体廓时,PTVCT对GTVCBCT的覆盖率分别为(66±35)％和(97±8)％(P=0.005)、(98±5)％和(99±2)％(P=0.034)及(98±4)％、(98±4)％(P=0.478).选择灰度配准方式和配准患侧时精度最佳,GTV的相似性指数为0.86±0.10,食管的为0.71±0.10,脊髓的为0.76±0.10,心脏的为0.89±0.05.GTV中心偏差为(0.25±0.16) cm.结论 肺癌放疗的CBCT引导摆位修正可满足临床要求,但较小配准范围会降低配准精度,建议采用配准患侧或配准体廓方式.
目的 比較和評估使用CBCT圖像引導襬位中不同圖像配準方法對配準精度的影響,為選擇閤理的圖像引導方法提供臨床依據.方法 對15例肺癌患者計劃CT和第1次放療襬位CBCT圖像分彆以不同算法(骨性或灰度配準)和不同範圍(靶區或患側或體廓)進行圖像配準,比較各組配準的治療體位下PTVCT對GTVCBCT的覆蓋率、靶區和OAR相似性指數及GTV幾何中心位置偏差.結果 相同配準範圍骨性配準精度差于灰度配準,其中配準靶區組差彆最明顯.骨性和灰度配準方式配準靶區、患側及體廓時,PTVCT對GTVCBCT的覆蓋率分彆為(66±35)％和(97±8)％(P=0.005)、(98±5)％和(99±2)％(P=0.034)及(98±4)％、(98±4)％(P=0.478).選擇灰度配準方式和配準患側時精度最佳,GTV的相似性指數為0.86±0.10,食管的為0.71±0.10,脊髓的為0.76±0.10,心髒的為0.89±0.05.GTV中心偏差為(0.25±0.16) cm.結論 肺癌放療的CBCT引導襬位脩正可滿足臨床要求,但較小配準範圍會降低配準精度,建議採用配準患側或配準體廓方式.
목적 비교화평고사용CBCT도상인도파위중불동도상배준방법대배준정도적영향,위선택합리적도상인도방법제공림상의거.방법 대15례폐암환자계화CT화제1차방료파위CBCT도상분별이불동산법(골성혹회도배준)화불동범위(파구혹환측혹체곽)진행도상배준,비교각조배준적치료체위하PTVCT대GTVCBCT적복개솔、파구화OAR상사성지수급GTV궤하중심위치편차.결과 상동배준범위골성배준정도차우회도배준,기중배준파구조차별최명현.골성화회도배준방식배준파구、환측급체곽시,PTVCT대GTVCBCT적복개솔분별위(66±35)％화(97±8)％(P=0.005)、(98±5)％화(99±2)％(P=0.034)급(98±4)％、(98±4)％(P=0.478).선택회도배준방식화배준환측시정도최가,GTV적상사성지수위0.86±0.10,식관적위0.71±0.10,척수적위0.76±0.10,심장적위0.89±0.05.GTV중심편차위(0.25±0.16) cm.결론 폐암방료적CBCT인도파위수정가만족림상요구,단교소배준범위회강저배준정도,건의채용배준환측혹배준체곽방식.
Objective To study the accuracy of different methods of CBCT image registration used in image-guided radiotherapy,and provide reasonable guidance for clinic application.Methods Planning CT and CBCT images acquired in first fraction of 15 lung cancer cases were studied,registered with different match method (bony/gray registration) and different match region (target only/ipsilateral structure/body).The CBCT target volume (GTVCBCT) coverage by planning target volume (PTVCT),the dice similarity coefficient (DSC) between the GTVCT and GTVCBCT and between the OARCT and OARCBCT,and the position deviation of the GTV geometric center were compared.Results The bony registration had worse precision,especially in the target only.The coverage ratio of PTVCT to GTVCBCT of bony and gray registration in the target only,ipsilateral structure,body group were (66 ± 35) ％ and (97 ± 8) ％ (P =0.005),(98 ± 5) ％and (99±2)％ (P=0.034),(98±4)％ and (98±4)％ (P=0.478),respectively.Using gray registration to register the ipsilateral structure had the best results,with the DSC of GTV and OARs of 0.86 ±0.10(GTV),0.71 ±0.10(esophagus),0.76 ±0.10(spinalcord),0.89 ±0.05 (heart),and the deviation of GTV center of (0.25 ± 0.16) cm.Conclusions Clinical positioning accuracy is achievable using CBCT guidance in lung cancer radiotherapy,and registering ipsilateral structure or body is recommend since small area registration is lack of accuracy.
