中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
EVALUATION AND ANAL YSIS OF DRUG-USE IN HOSPITALS OF CHINA
2015年
4期
469-471
,共3页
李娟%孙源博%王德平%王云枫
李娟%孫源博%王德平%王雲楓
리연%손원박%왕덕평%왕운풍
羟苯磺酸钙胶囊%单纯型糖尿病视网膜病变%疗效
羥苯磺痠鈣膠囊%單純型糖尿病視網膜病變%療效
간분광산개효낭%단순형당뇨병시망막병변%료효
Dobesilate calclum capsules%Simple diabetic retinopathy%Curative efficacy
目的：探讨羟苯磺酸钙胶囊治疗单纯型糖尿病视网膜病变的临床治疗效果。方法：选取牡丹江医学院附属红旗医院内分泌科2013年1月至2014年7月收治的单纯型糖尿病视网膜病变患者120例（210只眼），随机分为对照组和试验组。对照组患者给予常规治疗，试验组给予羟苯磺酸钙胶囊治疗。观察两组患者治疗前后视力和视网膜的变化（微血管瘤数量、出血、渗出和视网膜水肿）情况。结果：治疗后，与对照组相比，试验组患者眼底情况及视网膜恢复情况均有明显改善，两组差异具有统计学意义（P＜0．05）；试验组患者经过治疗后总有效率为57．3％，对照组总有效率为40．0％，两组比较差异具有统计学意义（P＜0．05）；试验组患者30°视野治疗效果明显优于对照组，视力得到明显提高和改善。结论：羟苯磺酸钙胶囊对促进单纯型糖尿病视网膜病变患者视力改善、眼底出血及渗出的吸收较常规治疗疗效明显，且安全性高，值得临床推广应用。
目的：探討羥苯磺痠鈣膠囊治療單純型糖尿病視網膜病變的臨床治療效果。方法：選取牡丹江醫學院附屬紅旂醫院內分泌科2013年1月至2014年7月收治的單純型糖尿病視網膜病變患者120例（210隻眼），隨機分為對照組和試驗組。對照組患者給予常規治療，試驗組給予羥苯磺痠鈣膠囊治療。觀察兩組患者治療前後視力和視網膜的變化（微血管瘤數量、齣血、滲齣和視網膜水腫）情況。結果：治療後，與對照組相比，試驗組患者眼底情況及視網膜恢複情況均有明顯改善，兩組差異具有統計學意義（P＜0．05）；試驗組患者經過治療後總有效率為57．3％，對照組總有效率為40．0％，兩組比較差異具有統計學意義（P＜0．05）；試驗組患者30°視野治療效果明顯優于對照組，視力得到明顯提高和改善。結論：羥苯磺痠鈣膠囊對促進單純型糖尿病視網膜病變患者視力改善、眼底齣血及滲齣的吸收較常規治療療效明顯，且安全性高，值得臨床推廣應用。
목적：탐토간분광산개효낭치료단순형당뇨병시망막병변적림상치료효과。방법：선취모단강의학원부속홍기의원내분비과2013년1월지2014년7월수치적단순형당뇨병시망막병변환자120례（210지안），수궤분위대조조화시험조。대조조환자급여상규치료，시험조급여간분광산개효낭치료。관찰량조환자치료전후시력화시망막적변화（미혈관류수량、출혈、삼출화시망막수종）정황。결과：치료후，여대조조상비，시험조환자안저정황급시망막회복정황균유명현개선，량조차이구유통계학의의（P＜0．05）；시험조환자경과치료후총유효솔위57．3％，대조조총유효솔위40．0％，량조비교차이구유통계학의의（P＜0．05）；시험조환자30°시야치료효과명현우우대조조，시력득도명현제고화개선。결론：간분광산개효낭대촉진단순형당뇨병시망막병변환자시력개선、안저출혈급삼출적흡수교상규치료료효명현，차안전성고，치득림상추엄응용。
OBJECTIVE:To explore the curative efficacy of dobesilate calcium capsules for simple diabetic retinopathy.METHODS:From January 2013 to July 2014, 120 patients (210 eyes) with diabetic retinopathy treated in the endocrinology department in Mudanjiang Medical College Hongqi Hospital Affiliated Hongqi Hospital were randomly divided into either control group receiving routine therapy or experiment group receiving dobesilate calcium capsules.Before and after treatment, visual acuity and the changes of retina (microaneurysms, hemorrhage, exudation and retinal edema) in the two groups were observed.RESULTS:After treatment, the fundus oculi and retina showed more significant improvement in the experimental group than in the control group, and the difference between the two groups was statistically significant ( P <0.05 ) .The total effective rate of the experiment group was 57.3% as compared with 40%of the control group, and the difference between the two groups was statistically significant ( P<0.05).The curative efficacy in 30°visual field showed better improvement in the experiment group than in the control group, and the visual acuity has been significantly improved.CONCLUSION:Dobesilate calcium capsule is safer and more effective than routine therapy in promoting improvement in visual acuity, fundus hemorrhage, absorption of the exudates in patients with simple lesions, with is thus worthy of wide clinical application.
