CAJ | 학술논문

目的：探讨不同酒精摄入量对脂肪肝发生率及其危险因素高血糖、高血脂等代谢紊乱的影响。方法选取2013年10—12月期间温州市中心医院体检中心394名体检人员进行问卷调查，并进行人体学和实验室指标测量作分析。结果经 LSD －t 检验，甘油三酯随着饮酒量增加而升高（P ＜0．05）；高甘油三酯、高尿酸、高胆固醇在不同饮酒量组间的检出率差异有统计学意义（P 均＜0．05），经卡方线性趋势检验显示，高甘油三酯及高尿酸患病率随着酒精摄入量增加而升高（P 均＜0．05）。饮酒量在脂肪肝和非脂肪肝的分布差异无统计学意义（P ＞0．05）。二项分类变量 Logistic 回归分析显示，腰臀比超标、高血压、超重肥胖、高甘油三酯血症为脂肪肝的独立危险因素，但未见“日均饮酒量”是脂肪肝的独立危险因素。结论腰臀比超标、高血压、超重肥胖、高甘油三酯血症是脂肪肝的危险因素，饮酒虽可导致高甘油三酯、高尿酸患病率升高，但未发现饮酒对脂肪肝患病率的直接影响。
목적：탐토불동주정섭입량대지방간발생솔급기위험인소고혈당、고혈지등대사문란적영향。방법선취2013년10—12월기간온주시중심의원체검중심394명체검인원진행문권조사，병진행인체학화실험실지표측량작분석。결과경 LSD －t 검험，감유삼지수착음주량증가이승고（P ＜0．05）；고감유삼지、고뇨산、고담고순재불동음주량조간적검출솔차이유통계학의의（P 균＜0．05），경잡방선성추세검험현시，고감유삼지급고뇨산환병솔수착주정섭입량증가이승고（P 균＜0．05）。음주량재지방간화비지방간적분포차이무통계학의의（P ＞0．05）。이항분류변량 Logistic 회귀분석현시，요둔비초표、고혈압、초중비반、고감유삼지혈증위지방간적독립위험인소，단미견“일균음주량”시지방간적독립위험인소。결론요둔비초표、고혈압、초중비반、고감유삼지혈증시지방간적위험인소，음주수가도치고감유삼지、고뇨산환병솔승고，단미발현음주대지방간환병솔적직접영향。
Objective To explore the relationship between alcohol drinking and fatty liver disease and its influencing factors.Methods From October to December,2013,a total of 394 people who underwent a physical examination in the medical examination center of Wenzhou central hospital were selected for this study.Anthroposomatology measurement and biochemical tests were conducted.Results There were significantly statistical differences of triglyceride,uric acid and cholesterol in different drinking groups (P <0.05).The prevalence of high triglyceride and uric acid were increased with alcohol consumption (P <0.05).There was no significant difference of alcohol consumption between fatty liver and non -fatty liver group (P =0.42).Logistic regression showed that waist -hip ratio,hypertension,overweight,obesity and hypertriglyceridemia were risk factors of fatty liver,while daily alcohol consumption cannot be thought as risk factor yet. Conclusion Waist -hip ratio,hypertension,overweight -obesity and hypertriglyceridemia were the risk factors of fatty liver.Alcohol consumption could contribute to the prevalence of triglyceride and uric acid.