CAJ | 학술논문

MicroRNA (miRNA)是一类大小约21～25 nt,广泛存在于真核生物和各种病毒体内的非蛋白编码单链小分子RNA,是转录后水平的细胞调控因子.miRNA广泛参与真核生物细胞的生长、发育、代谢、凋亡等生理活动.miRNA也广泛参与血吸虫生长发育及生理代谢过程,在血吸虫感染早期,miRNA在血吸虫和宿主之间起到了非常重要的作用.该文就miRNA在血吸虫病致病机制中的作用作一综述.
MicroRNA (miRNA)시일류대소약21～25 nt,엄범존재우진핵생물화각충병독체내적비단백편마단련소분자RNA,시전록후수평적세포조공인자.miRNA엄범삼여진핵생물세포적생장、발육、대사、조망등생리활동.miRNA야엄범삼여혈흡충생장발육급생리대사과정,재혈흡충감염조기,miRNA재혈흡충화숙주지간기도료비상중요적작용.해문취miRNA재혈흡충병치병궤제중적작용작일종술.
MicroRNAs (miRNAs) are noncoding RNAs,21～25 nt in length,that widely exist in eukaryotic and a variety of virus.MiRNAs regulate the cell functions in the post-transcription level.MiRNAs widely participate in the cell growth,development,metabolism,apoptosis and other biological process of eukaryotic cells.Moreover,miRNAs are involved in the development of schistosome and its physiological metabolic process.In the early stage of schistosome infection,miRNAs play a vital role between schistosome and the host.In this review,the roles of miRNAs in the pathogenic mechanism of schistosomiasis were summarized.