中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
12期
94-96
,共3页
杨茗%李云秀%柏智%纪艳洁
楊茗%李雲秀%柏智%紀豔潔
양명%리운수%백지%기염길
产后出血%瘢痕子宫阴道分娩%卡前列素氨丁三醇%卡前列甲酯
產後齣血%瘢痕子宮陰道分娩%卡前列素氨丁三醇%卡前列甲酯
산후출혈%반흔자궁음도분면%잡전렬소안정삼순%잡전렬갑지
Postpartum hemorrhage%Scar uterus vaginal delivery%Romethamine%Carboprost methylate
目的：探讨卡前列素氨丁三醇与卡前列甲酯在预防瘢痕子宫阴道分娩产后出血中的效果对比。方法选择本院2013年1月~2014年12月收治的瘢痕子宫阴道分娩产妇120例，随机分为观察组和对照组，各60例。对照组产妇于胎儿娩出后肌内注射缩宫素20 U，同时给予卡前列甲酯1 mg舌下含服；观察组于胎儿娩出后肌内注射缩宫素20 U和卡前列素氨丁三醇250μg，对比两组产后2、24 h出血量及第三产程、产后出血发生率、不良反应发生率。结果观察组产后2、24 h出血量为（223.62±92.40）、（322.08±92.40）ml，少于对照组的（285.00±120.10）、（387.10±127.07）ml，差异有统计学意义（P<0.05）。观察组第三产程时间为（6.87±1.60）min，短于对照组的（8.77±2.07）min，差异有统计学意义（P<0.05）；观察组产后出血发生率（3.33%）低于对照组（13.33%），差异有统计学意义（P<0.05）；两组不良反应发生率比较差异无统计学意义（P>0.05）。讨论卡前列素氨丁三醇预防瘢痕子宫阴道分娩产后出血的效果优于卡前列甲酯，值得临床推广应用。
目的：探討卡前列素氨丁三醇與卡前列甲酯在預防瘢痕子宮陰道分娩產後齣血中的效果對比。方法選擇本院2013年1月~2014年12月收治的瘢痕子宮陰道分娩產婦120例，隨機分為觀察組和對照組，各60例。對照組產婦于胎兒娩齣後肌內註射縮宮素20 U，同時給予卡前列甲酯1 mg舌下含服；觀察組于胎兒娩齣後肌內註射縮宮素20 U和卡前列素氨丁三醇250μg，對比兩組產後2、24 h齣血量及第三產程、產後齣血髮生率、不良反應髮生率。結果觀察組產後2、24 h齣血量為（223.62±92.40）、（322.08±92.40）ml，少于對照組的（285.00±120.10）、（387.10±127.07）ml，差異有統計學意義（P<0.05）。觀察組第三產程時間為（6.87±1.60）min，短于對照組的（8.77±2.07）min，差異有統計學意義（P<0.05）；觀察組產後齣血髮生率（3.33%）低于對照組（13.33%），差異有統計學意義（P<0.05）；兩組不良反應髮生率比較差異無統計學意義（P>0.05）。討論卡前列素氨丁三醇預防瘢痕子宮陰道分娩產後齣血的效果優于卡前列甲酯，值得臨床推廣應用。
목적：탐토잡전렬소안정삼순여잡전렬갑지재예방반흔자궁음도분면산후출혈중적효과대비。방법선택본원2013년1월~2014년12월수치적반흔자궁음도분면산부120례，수궤분위관찰조화대조조，각60례。대조조산부우태인면출후기내주사축궁소20 U，동시급여잡전렬갑지1 mg설하함복；관찰조우태인면출후기내주사축궁소20 U화잡전렬소안정삼순250μg，대비량조산후2、24 h출혈량급제삼산정、산후출혈발생솔、불량반응발생솔。결과관찰조산후2、24 h출혈량위（223.62±92.40）、（322.08±92.40）ml，소우대조조적（285.00±120.10）、（387.10±127.07）ml，차이유통계학의의（P<0.05）。관찰조제삼산정시간위（6.87±1.60）min，단우대조조적（8.77±2.07）min，차이유통계학의의（P<0.05）；관찰조산후출혈발생솔（3.33%）저우대조조（13.33%），차이유통계학의의（P<0.05）；량조불량반응발생솔비교차이무통계학의의（P>0.05）。토론잡전렬소안정삼순예방반흔자궁음도분면산후출혈적효과우우잡전렬갑지，치득림상추엄응용。
Objective To investigate the curative effect comparison of romethamine and carboprost methylate in pre-vention of postpartum hemorrhage of scar uterus vaginal delivery. Methods 120 women with scar uterus vaginal deliv-ery in our hospital from January 2013 to December 2014 were selected and randomly divided into observation group and control group,60 cases in each group.After delivery of fetus,control group were given with oxytocin intramuscular injection 20 U and carboprost methylate sublingual 1 mg at the same time,observation group were given with oxytocin intramuscular 20 U and romethamine 250μg injection.The amount of bleeding in 2,24 h after delivery,third stage of la-bor,incidence rate of postpartum hemorrhage and adverse reaction were compared between two groups of postpartum. Results In observation group,the amount of bleeding in 2,24 h after delivery was (223.62±92.40),(322.08±92.40) ml re-spectively,less than that in control group[(285.00±120.10),(387.10±127.07) ml] respectively,with significant difference(P<0.05).Third stage of labor in observation group[(6.87±1.60) min] was shorter than that in control group[(8.77±2.07) min], with significant difference(P<0.05).The incidence rate of postpartum hemorrhage in observation group(3.33%) was lower than that in control group (13.33%),with significant difference (P<0.05).There was no statistical difference in the inci-dence rate of adverse reaction between two groups(P>0.05). Conclusion Romethamine prevention of postpartum hemor-rhage of scar uterus vaginal delivery is better than carboprost methylate.It is worthy of clinical promotion and application.
