中国美容医学
中國美容醫學
중국미용의학
CHINESE JOURNAL OF AESTHETIC MEDICINE
2015年
7期
31-34
,共4页
重组人表皮生长因子%颌面创伤%疗效
重組人錶皮生長因子%頜麵創傷%療效
중조인표피생장인자%합면창상%료효
recombinant human epidermal growth factor(rhEGF)%maxillofacial trauma%efficacy
目的：观察重组人表皮生长因子（recombinant human epidermal growth factor ，rhEGF）对口腔颌面部外伤创面的疗效情况。方法：采用整形美容缝合技术处理伤口后，治疗组创面喷洒rhEGF ，再用rhEGF将适当大小消毒油纱喷湿或浸湿敷于创面,外层覆盖干纱布包扎。两组前3天每天换药1次,3天后根据情况隔天或3天换药1次,并同时口服抗生素,对照组采用消毒油纱敷于伤口,其他治疗同观察组,观察两组创面愈合时间及瘢痕增生情况。结果：rhEGF治疗组愈合时间(5.21±2.14)天，对照组愈合时间(7.43±2.46)天，治疗组比对照组明显缩短；治疗组瘢痕发生率为3.22%，对照组瘢痕发生率17.74%，差异有统计学意义(P<0.01)；创面愈合质量比对照组好,瘢痕发生率低。结论：rhEGF能显著加快皮肤生长,缩短皮肤愈合时间,减轻瘢痕形成。
目的：觀察重組人錶皮生長因子（recombinant human epidermal growth factor ，rhEGF）對口腔頜麵部外傷創麵的療效情況。方法：採用整形美容縫閤技術處理傷口後，治療組創麵噴灑rhEGF ，再用rhEGF將適噹大小消毒油紗噴濕或浸濕敷于創麵,外層覆蓋榦紗佈包扎。兩組前3天每天換藥1次,3天後根據情況隔天或3天換藥1次,併同時口服抗生素,對照組採用消毒油紗敷于傷口,其他治療同觀察組,觀察兩組創麵愈閤時間及瘢痕增生情況。結果：rhEGF治療組愈閤時間(5.21±2.14)天，對照組愈閤時間(7.43±2.46)天，治療組比對照組明顯縮短；治療組瘢痕髮生率為3.22%，對照組瘢痕髮生率17.74%，差異有統計學意義(P<0.01)；創麵愈閤質量比對照組好,瘢痕髮生率低。結論：rhEGF能顯著加快皮膚生長,縮短皮膚愈閤時間,減輕瘢痕形成。
목적：관찰중조인표피생장인자（recombinant human epidermal growth factor ，rhEGF）대구강합면부외상창면적료효정황。방법：채용정형미용봉합기술처리상구후，치료조창면분쇄rhEGF ，재용rhEGF장괄당대소소독유사분습혹침습부우창면,외층복개간사포포찰。량조전3천매천환약1차,3천후근거정황격천혹3천환약1차,병동시구복항생소,대조조채용소독유사부우상구,기타치료동관찰조,관찰량조창면유합시간급반흔증생정황。결과：rhEGF치료조유합시간(5.21±2.14)천，대조조유합시간(7.43±2.46)천，치료조비대조조명현축단；치료조반흔발생솔위3.22%，대조조반흔발생솔17.74%，차이유통계학의의(P<0.01)；창면유합질량비대조조호,반흔발생솔저。결론：rhEGF능현저가쾌피부생장,축단피부유합시간,감경반흔형성。
Objective To observe the efficacy of recombinant human epidermal growth factor on oral and maxillofacial traumatic wound. Methods Using cosmetic suture technique to the treatment of wounds,wound in the treatment group was sprayed with rhEGF,then rhEGF will be appropriate to the size of the disinfection oil gauze jet wet or wet dressing on the wound,the outer covering of dry gauze bandage.The two groups before 3 days change medicine 1 times,3 days according to the next day or 3 days change medicine 1 times,and oral antibiotics,the control group used disinfection oil gauze in the wound,the other the same treatment as observation group, the two groups were observed and the time of wound healing and scar hyperplasia. Results The healing time rhEGF treatment group was (5.21 ± 2.14)d,the control group was (7.43 ± 2.46) d,the treatment group was significantly shorter than the control group.the treatment group scar formation rate was 3.22%,control group,scar formation rate 17.74,the difference was statistically significant(P<0.01).Wound healing quality was better than the control group,and the scar formation rate was low. Conclusion rhEGF can significantly speed up the skin growth,shorten the healing time of skin,significantly reduce scar formation.
