CAJ | 학술논문

主要采用 DAB 免疫组织化学方法对离子型谷氨酸受体 AMPA 亚型 GluR2在成年雄性斑胸草雀(Taeniopygia guttata )鸣唱系统的分布进行了研究。结果显示：1)端脑高级发声中枢 HVC(proper name)中,GluR2表达丰富,并主要分布于胞体部位；在 HVC 投射至弓状皮质栎核(robust nucleus of the arcopallium,RA)的路径上,有大量的GluR2阳性细胞分布,并有少量阳性纤维分布；2)RA 中,呈密集的 GluR2阳性胞体标记；3)前脑基底神经节 X 区(Area X)中,有少量阳性胞体标记；4)中脑腹侧被盖区(ventral tegmental area,VTA)、黑质致密部(substantia nigra compacta, SNc)存在大量的阳性胞体标记。本实验结果表明 GluR2可能参与了鸣唱运动的调控和维持。
주요채용 DAB 면역조직화학방법대리자형곡안산수체 AMPA 아형 GluR2재성년웅성반흉초작(Taeniopygia guttata )명창계통적분포진행료연구。결과현시：1)단뇌고급발성중추 HVC(proper name)중,GluR2표체봉부,병주요분포우포체부위；재 HVC 투사지궁상피질력핵(robust nucleus of the arcopallium,RA)적로경상,유대량적GluR2양성세포분포,병유소량양성섬유분포；2)RA 중,정밀집적 GluR2양성포체표기；3)전뇌기저신경절 X 구(Area X)중,유소량양성포체표기；4)중뇌복측피개구(ventral tegmental area,VTA)、흑질치밀부(substantia nigra compacta, SNc)존재대량적양성포체표기。본실험결과표명 GluR2가능삼여료명창운동적조공화유지。
Immnuohistochemistry revealed that GluR2 was strongly expressed in song system in adult male zebra finches.It was found that high vocal center HVC showed rich GluR2 labeling in soma.A large number of GluR2 positive cells and poorly stalned fibers from HVC path projected to robust nucleus of arcopallium (RA). Strong GluR2-positive cells were found and densely distributed in RA.Basal ganglia X area (Area X)showed a small amount of positive cell bodies.The ventral tegmental area (VTA)and ubstantia nigra compacta (SNc) showed a great number of GluR2 positive cell bodies.These data suggest that GluR2 may be involved in regulating vocal learning and malntenance in songbirds.