CAJ | 학술논문

赭曲霉毒素（OTA）具有细胞毒性，免疫抑制作用和抑制DNA和RNA合成，因此建立一种快速灵敏的方法检测OTA成为热门的研究方向.本文以掺杂Al3+离子作为改性剂制备的分子印迹聚合物修饰的电化学传感器. Al3+与模板分子产生强的配位作用，这种配位作用有效的提高了掺杂分子印迹聚合物的印迹效率.①
자곡매독소（OTA）구유세포독성，면역억제작용화억제DNA화RNA합성，인차건립일충쾌속령민적방법검측OTA성위열문적연구방향.본문이참잡Al3+리자작위개성제제비적분자인적취합물수식적전화학전감기. Al3+여모판분자산생강적배위작용，저충배위작용유효적제고료참잡분자인적취합물적인적효솔.①
Sensitive and fast methods for the detection of OTA toxin (OTA),which has cytotoxic and immunosuppressive effects in DNA and RNA synthesis,are highly desirable and have become a topic of intense research. A sensitive molecularly imprinted electrochemical sensor was constructed for the selective detection of OTA. In this study,the aluminium ions (Al3+) was used as a modifier to prepare a selective biosensor modified with a molecularly imprinted metallo-polymers. With the increased coordination of the metal ions and templates,the selectivity and sensitivity of the MIPs were effectively improved.