CAJ | 학술논문

目的：探讨早期胃管灌注硫酸镁对急性胆源性胰腺炎患者白细胞、淀粉酶及急诊手术率的影响。方法选取该院于2009年8月－2014年8月收治的133例急性胆原性胰腺炎患者为研究对象，随机分成A组（ n＝67）与B组（n＝66）2组。 B组采用常规非手术疗法进行治疗，A组在上述治疗基础上辅以早期胃管灌注硫酸镁疗法进行治疗。观察分析2组患者治疗后淀粉酶、体温等各项指标降低率、自主排便率及急诊手术率对比情况；记录其疼痛缓解情况。结果①A组治疗后WBC、淀粉酶等指标降低率、急诊手术发生率及自主排便率均高于B组患者，组间对比差异明显（P＜0．05）；②治疗后，A组患者VAS评分为（2．3±1．1）分，明显低于B组患者的（5．2±1．8）分，组间对比具有统计学意义（P＜0．05）。结论对早期急性胆源性胰腺炎患者采用胃管灌注硫酸镁疗法，可有效缓解其部分早期症状，减少治疗后24 h内急诊手术发生率，利于患者自主排便，能加速胆管结石排除，缓解括约肌痉挛情况，对改善患者临床症状、减轻病痛等具有积极意义。
목적：탐토조기위관관주류산미대급성담원성이선염환자백세포、정분매급급진수술솔적영향。방법선취해원우2009년8월－2014년8월수치적133례급성담원성이선염환자위연구대상，수궤분성A조（ n＝67）여B조（n＝66）2조。 B조채용상규비수술요법진행치료，A조재상술치료기출상보이조기위관관주류산미요법진행치료。관찰분석2조환자치료후정분매、체온등각항지표강저솔、자주배편솔급급진수술솔대비정황；기록기동통완해정황。결과①A조치료후WBC、정분매등지표강저솔、급진수술발생솔급자주배편솔균고우B조환자，조간대비차이명현（P＜0．05）；②치료후，A조환자VAS평분위（2．3±1．1）분，명현저우B조환자적（5．2±1．8）분，조간대비구유통계학의의（P＜0．05）。결론대조기급성담원성이선염환자채용위관관주류산미요법，가유효완해기부분조기증상，감소치료후24 h내급진수술발생솔，리우환자자주배편，능가속담관결석배제，완해괄약기경련정황，대개선환자림상증상、감경병통등구유적겁의의。
Objective To discuss the effects of leukocytes , amylase and emergency operation rate of patients with acute biliary pancreatitis treated by early-phase stomach tube infusion of magnesium sulfate . Method 133casesofpatientswithacutebiliarypancreatitistreatedinourhospitalfromAugust2009to August 2014 were selected as the study objects .They were randomly divided into group A with 67 cases and group B with 66 cases.Patients in group B were given regular non-operative treatment , while those in group A were given early-phase stomach tube infusion of magnesium sulfate treatment combined with the aforementioned treatment .The decrease rate , independent defecation rate and emergency operation rate of amylase , temperature and other indexes were observed and analyzed of the two groups .Meanwhile , the easement rate of pain was recorded .Results After treatment, firstly, WBC, the decrease rate of amyl-ase and other common indexes , emergency operation rate and independent defecation rate in group A were all higher than those in group B and the differences between groups have a statistical significance ( P<0.05).Secondly, the VAS score of group A was (2.3 ±1.1), which was obviously lower than that of group B’s 5.2 ±1.8) and the differences between groups have statistical significance (P<0.05).Con-clusion Applying early-phase stomach tube infusion of magnesium sulfate to patients with acute biliary pancreatitis can effectively remit incipient symptoms to some extent , decrease the emergency operation rate within 24 hours after treatment , be beneficial to independent defecation of patients , accelerate the elimination of calculus of bile duct , ease sphincter spasm and better improve clinical symptoms of patients and relieve pain .