CAJ | 학술논문

目的：探讨单纯性低甲状腺素血症对妊娠结局的影响。方法随访妊娠早中期妇女3131例，其中单纯性低甲状腺素血症孕妇77例（观察组），甲状腺功能正常且甲状腺自身抗体阴性的孕妇3054例（对照组），比较两组不良妊娠结局发生率的差异。结果观察组妊娠期糖尿病、妊娠期高血压、前置胎盘、胎盘早剥、胎儿宫内发育迟缓、胎儿宫内窘迫、死胎、出生时外观畸形、胎膜早破、早产、低体重儿发生率均无统计学差异（χ2值分别为1．026、0．060、8．483、8．483、0．789、1．619、0．177、1．490、1．438、0．077、0，均P＞0．05）。结论单纯性低甲状腺素血症不增加不良妊娠结局的发生率。
목적：탐토단순성저갑상선소혈증대임신결국적영향。방법수방임신조중기부녀3131례，기중단순성저갑상선소혈증잉부77례（관찰조），갑상선공능정상차갑상선자신항체음성적잉부3054례（대조조），비교량조불량임신결국발생솔적차이。결과관찰조임신기당뇨병、임신기고혈압、전치태반、태반조박、태인궁내발육지완、태인궁내군박、사태、출생시외관기형、태막조파、조산、저체중인발생솔균무통계학차이（χ2치분별위1．026、0．060、8．483、8．483、0．789、1．619、0．177、1．490、1．438、0．077、0，균P＞0．05）。결론단순성저갑상선소혈증불증가불량임신결국적발생솔。
Objective To evaluate the influence of isolated hypothyroxinemia on pregnant outcomes.Methods Totally 3 131 women at early or middle pregnancy were followed up.The occurrence of adverse pregnant outcomes was compared between observation group (77 cases with isolated hypothyroxinemia) and control group (3 054 euthyroid cases with negative antibody).Results There was no significant difference between two groups in the incidence rate of gestational diabetes mellitus, gestational hypertension, placenta previa, placental abruption, intrauterine growth restriction, fetal distress, stillbirth, malformation, premature rupture of membranes, premature delivery and low birth (χ2 value was 1.026, 0.060, 8.483, 8.483, 0.789, 1.619, 0.177, 1.490, 1.438 and 0.077, respectively, all P>0.05). Conclusion Isolated hypothyroxinemia will not increase the incidence rate of adverse pregnant outcomes.