CAJ | 학술논문

目的：探讨中药组方双黄益智汤治疗血管性痴呆的临床疗效。方法102例血管性痴呆患者随机分为两组，对照组50例口服茴拉西坦、尼莫地平治疗。治疗组给予双黄益智汤治疗，3个月为1个疗程，1个疗程后观察两组治疗前后的简易智能状态量表（ MMSE ）评分、日常生活量表（ ADL）评分、中医证候评分及血脂水平变化。结果治疗组治疗后中医证候评分、MMSE评分、ADL评分改善均优于对照组（ P﹤0.05，P﹤0.01）。经过3个月的治疗，治疗组血甘油三脂、总胆固醇水平低于对照组（ P﹤0.05）。结论中药组方双黄益智汤能有效治疗血管性痴呆，且能降低血脂水平。
목적：탐토중약조방쌍황익지탕치료혈관성치태적림상료효。방법102례혈관성치태환자수궤분위량조，대조조50례구복회랍서탄、니막지평치료。치료조급여쌍황익지탕치료，3개월위1개료정，1개료정후관찰량조치료전후적간역지능상태량표（ MMSE ）평분、일상생활량표（ ADL）평분、중의증후평분급혈지수평변화。결과치료조치료후중의증후평분、MMSE평분、ADL평분개선균우우대조조（ P﹤0.05，P﹤0.01）。경과3개월적치료，치료조혈감유삼지、총담고순수평저우대조조（ P﹤0.05）。결론중약조방쌍황익지탕능유효치료혈관성치태，차능강저혈지수평。
Objective To explore the clinical efficacy of shuanghuang yizhi decoction on vascular dementia. Methods One hundred and two cases of vascular dementia were randomized into two groups. In the control group(50 cases),aniracetam and nimodipine were prescribed for oral administration. In the treat-ment group,shuanghuang yizhi decoction was applied. The treatment for 3 months made 1 session for adminis-tration. MMSE and ADL scores,TCM syndrome score and blood lipid level were observed before and after treatment. Results After treatment,the improvements in TCM syndrome score,MMSE score and ADL score in the treatment group were better than those in the control group(P﹤0. 05,P﹤0. 01). After 3 months treat-ment,the levels of TG and TCHO in the treatment were all lower than those in the control group(P﹤0. 05). Conclusion Shuanghuang yizhi decoction effectively treats vascular dementia and reduces blood lipid level.