中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
11期
119-122
,共4页
白内障扶贫复明活动%小切口白内障术%角膜2~3级水肿%临床疗效
白內障扶貧複明活動%小切口白內障術%角膜2~3級水腫%臨床療效
백내장부빈복명활동%소절구백내장술%각막2~3급수종%림상료효
Activity of cataract supporting the poor and regaining the sight%Small-incision cataract surgery%Corneal edema in gradeII-Ⅲ%Clinical efficacy
目的：探讨小切口白内障术后角膜2~3级水肿的临床治疗效果。方法选取2009年6月~2014年2月在本院进行白内障摘除术后角膜2~3级水肿的340例患者400眼，随机分为观察组和对照组，观察组采用10 ml 10%氯化钠溶液+5 mg地塞米松(1 ml)+维生素C 500 mg 1支，雾化喷眼，并用10%氯化钠溶液加入氯霉素滴眼液空瓶中滴眼(4次/d)+妥布霉素地塞米松滴眼液滴眼(1滴/30 min)，每晚四环素可的松眼膏睡前涂眼。对照组予妥布霉素地塞米松滴眼液滴眼，1滴/30 min，每晚四环素可的松眼膏睡前涂眼。两组患者角膜水肿转为1级后出院门诊随诊观察。结果观察组2级角膜水肿患者术后第3天好转率明显高于对照组，差异有统计学意义(χ2=42.63，P=0.0000)，术后第7天治愈率明显高于对照组，差异有统计学意义(χ2=98.05，P=0.0000)；观察组3级角膜水肿患者术后第3天及术后第7天好转率明显高于对照组，差异有统计学意义(χ2=37.62、8.95，P=0.0000)。结论观察组采用的治疗小切口白内障术后角膜2~3级水肿的药物较为普通，临床治疗效果显著，治疗方案值得在白内障扶贫复明活动中推广。
目的：探討小切口白內障術後角膜2~3級水腫的臨床治療效果。方法選取2009年6月~2014年2月在本院進行白內障摘除術後角膜2~3級水腫的340例患者400眼，隨機分為觀察組和對照組，觀察組採用10 ml 10%氯化鈉溶液+5 mg地塞米鬆(1 ml)+維生素C 500 mg 1支，霧化噴眼，併用10%氯化鈉溶液加入氯黴素滴眼液空瓶中滴眼(4次/d)+妥佈黴素地塞米鬆滴眼液滴眼(1滴/30 min)，每晚四環素可的鬆眼膏睡前塗眼。對照組予妥佈黴素地塞米鬆滴眼液滴眼，1滴/30 min，每晚四環素可的鬆眼膏睡前塗眼。兩組患者角膜水腫轉為1級後齣院門診隨診觀察。結果觀察組2級角膜水腫患者術後第3天好轉率明顯高于對照組，差異有統計學意義(χ2=42.63，P=0.0000)，術後第7天治愈率明顯高于對照組，差異有統計學意義(χ2=98.05，P=0.0000)；觀察組3級角膜水腫患者術後第3天及術後第7天好轉率明顯高于對照組，差異有統計學意義(χ2=37.62、8.95，P=0.0000)。結論觀察組採用的治療小切口白內障術後角膜2~3級水腫的藥物較為普通，臨床治療效果顯著，治療方案值得在白內障扶貧複明活動中推廣。
목적：탐토소절구백내장술후각막2~3급수종적림상치료효과。방법선취2009년6월~2014년2월재본원진행백내장적제술후각막2~3급수종적340례환자400안，수궤분위관찰조화대조조，관찰조채용10 ml 10%록화납용액+5 mg지새미송(1 ml)+유생소C 500 mg 1지，무화분안，병용10%록화납용액가입록매소적안액공병중적안(4차/d)+타포매소지새미송적안액적안(1적/30 min)，매만사배소가적송안고수전도안。대조조여타포매소지새미송적안액적안，1적/30 min，매만사배소가적송안고수전도안。량조환자각막수종전위1급후출원문진수진관찰。결과관찰조2급각막수종환자술후제3천호전솔명현고우대조조，차이유통계학의의(χ2=42.63，P=0.0000)，술후제7천치유솔명현고우대조조，차이유통계학의의(χ2=98.05，P=0.0000)；관찰조3급각막수종환자술후제3천급술후제7천호전솔명현고우대조조，차이유통계학의의(χ2=37.62、8.95，P=0.0000)。결론관찰조채용적치료소절구백내장술후각막2~3급수종적약물교위보통，림상치료효과현저，치료방안치득재백내장부빈복명활동중추엄。
Objective To explore the clinical therapeutic effect of corneal edema in grade II-Ⅲ after small-incision cataract surgery. Methods 340 cases of patients (400 eyes) suffered from corneal edema in grade II-Ⅲ after cataract surgery in our hospital from June 2009 to February 2014 were randomly divided into observation group and control group.In the observation group,10 ml 10% sodium chloride solution,5 mg dexamethasone (1 ml),and 500 mg vitamin C were mixed for atomization sparging eyes.10% sodium chloride solution was put into empty bottle of chloramphenicol eye drops for eye drops four times per day.Tobramycin and dexamethasone eye drop was also used for eye drops every 30 min per drip.Tetracycline cortisone eye ointment was painted for eyes before sleep every night.In the control group, only tobramycin and dexamethasone eye drop which was also used for eye drops (every 30 min per drip) and tetracy-cline cortisone eye ointment which was painted for eyes before sleep every night were selected.Patients in both groups were discharged from hospital and classified into outpatient follow-up observation when corneal edema turned into grade Ⅰ. Results Postoperative improvement rate in the third day in patients with corneal edema in grade II in the observation group was higher than that in the control group,the difference was significant (χ2=42.63,P=0.0000).The cure rate in the 7th day in patients with corneal edema in grade II in the observation group was higher than that in the control group,the difference was significant (χ2=98.05,P=0.0000).Postoperative improvement rate in the 3rd and 7th day in patients with corneal edema in grade Ⅲ in the observation group was higher than that in the control group,the differ-ence was significant (χ2=37.62,8.95,P=0.0000). Con-clusion The drugs used for corneal edema in grade II-Ⅲ after small-incision cataract surgery are very com-mon and their therapeutic effects are very obvious.The therapeutic regimen in the observation group is worthy of expansion in the activity of cataract supporting the poor and regaining the sight.
