中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2015年
2期
374-375
,共2页
甲氨蝶呤%清宫术%子宫瘢痕处妊娠%疗效
甲氨蝶呤%清宮術%子宮瘢痕處妊娠%療效
갑안접령%청궁술%자궁반흔처임신%료효
Methotrexate%curettage%caesarean scar pregnancy%curative effect
目的:评价甲氨蝶呤妊娠囊内注射联合清宫术治疗子宫瘢痕处妊娠的临床效果。方法收集2010年8月至2013年8月广西贺州市人民医院收治的子宫瘢痕处妊娠患者20例作为观察组,并选取同时住院的20例患者作为对照组,观察组给予甲氨蝶呤妊娠囊内注射联合清官术进行治疗,对照组给予妊娠囊内注射甲氨蝶呤。所有患者每隔3d测定血β–人绒毛膜促性腺激素(β-hCG),对比分析两组患者血β-hCG回归到正常值的时间、住院时间、治疗费用。结果观察组患者血β-hCG降到正常值的时间、住院时间、住院费用均显著低于对照组(t值分别为22.27、11.97、141.46,均P<0.05)。观察组治疗总有效率(95%)显著高于对照组(70%),χ2=4.329,P<0.05。结论甲氨蝶呤妊娠囊内注射联合清宫术治疗子宫瘢痕处妊娠疗效显著,且住院时间较短、治疗费用低,具有较大的临床推广价值。
目的:評價甲氨蝶呤妊娠囊內註射聯閤清宮術治療子宮瘢痕處妊娠的臨床效果。方法收集2010年8月至2013年8月廣西賀州市人民醫院收治的子宮瘢痕處妊娠患者20例作為觀察組,併選取同時住院的20例患者作為對照組,觀察組給予甲氨蝶呤妊娠囊內註射聯閤清官術進行治療,對照組給予妊娠囊內註射甲氨蝶呤。所有患者每隔3d測定血β–人絨毛膜促性腺激素(β-hCG),對比分析兩組患者血β-hCG迴歸到正常值的時間、住院時間、治療費用。結果觀察組患者血β-hCG降到正常值的時間、住院時間、住院費用均顯著低于對照組(t值分彆為22.27、11.97、141.46,均P<0.05)。觀察組治療總有效率(95%)顯著高于對照組(70%),χ2=4.329,P<0.05。結論甲氨蝶呤妊娠囊內註射聯閤清宮術治療子宮瘢痕處妊娠療效顯著,且住院時間較短、治療費用低,具有較大的臨床推廣價值。
목적:평개갑안접령임신낭내주사연합청궁술치료자궁반흔처임신적림상효과。방법수집2010년8월지2013년8월엄서하주시인민의원수치적자궁반흔처임신환자20례작위관찰조,병선취동시주원적20례환자작위대조조,관찰조급여갑안접령임신낭내주사연합청관술진행치료,대조조급여임신낭내주사갑안접령。소유환자매격3d측정혈β–인융모막촉성선격소(β-hCG),대비분석량조환자혈β-hCG회귀도정상치적시간、주원시간、치료비용。결과관찰조환자혈β-hCG강도정상치적시간、주원시간、주원비용균현저저우대조조(t치분별위22.27、11.97、141.46,균P<0.05)。관찰조치료총유효솔(95%)현저고우대조조(70%),χ2=4.329,P<0.05。결론갑안접령임신낭내주사연합청궁술치료자궁반흔처임신료효현저,차주원시간교단、치료비용저,구유교대적림상추엄개치。
Objective To estimate the clinical effect of gestational sac injection of Methotrexate combined with curettage on treatment of caesarean scar pregnancy.Methods Totally 20 cases of caesarean scar pregnancy treated in Hezhou People’ s Hospital during the period of August 2010 to August 2013 were selected in observation group, and another 20 cases hospitalized in the same period were recruited in control group.Treatment of gestational sac injection of Methotrexate combined with curettage was given to the observation group, while the control group only received gestational sac injection of Methotrexate.The blood β-hCG level was monitored every 3 days.The time of β-hCG dropping to normal level, hospitalization length and cost of treatment were compared between two groups.Results The time ofβ-hCG dropping to normal level, hospital staying and cost of treatment in the observation group were significantly shorter and lower than those in the control group (t value was 22.27, 11.97 and 141.46, respectively, all P<0.05).The total effective rate of the observation group (95%) was significantly higher than that of the control group (70%) (χ2 =42.43,P<0.05).Conclusion Gestational sac injection of Methotrexate combined with curettage is effective on caesarean scar pregnancy, which has the advantages of short hospital stay and low treatment cost.It is worthy of clinical application.