中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2015年
11期
61-62,65
,共3页
食管癌%术前半量放疗%临床效果
食管癌%術前半量放療%臨床效果
식관암%술전반량방료%림상효과
Esophagus cancer%Half-dose radiotherapy in pre-operation%Effect observation
目的：探讨食管癌术前半量放疗的临床效果。方法选取本院肿瘤科2012年4月~2013年4月收治的80例食管癌患者作为研究对象，其中可采取直接手术的40例设为对照组，40例需术前半量放疗再行手术的设为观察组。比较两组的临床总切除术率、根除术切除率、区域淋巴结转移率、断端残癌阳性率及随访1年生存率，观察相关并发症发生的情况。结果观察组的临床总切除术率、根除术切除率和随访1年生存率明显高于对照组，区域淋巴结转移率和断端残癌阳性率明显低于对照组，差异有统计学意义(P<0.05)；观察组的总并发症发生率为10.0%，明显低于对照组的15.0%，差异有统计学意义(P<0.05)。结论食管癌术前行半量放疗，可改善患者的生活质量，延长生存期，减少转移和复发，延长远期生存率，对保障患者预后有非常重要的意义。
目的：探討食管癌術前半量放療的臨床效果。方法選取本院腫瘤科2012年4月~2013年4月收治的80例食管癌患者作為研究對象，其中可採取直接手術的40例設為對照組，40例需術前半量放療再行手術的設為觀察組。比較兩組的臨床總切除術率、根除術切除率、區域淋巴結轉移率、斷耑殘癌暘性率及隨訪1年生存率，觀察相關併髮癥髮生的情況。結果觀察組的臨床總切除術率、根除術切除率和隨訪1年生存率明顯高于對照組，區域淋巴結轉移率和斷耑殘癌暘性率明顯低于對照組，差異有統計學意義(P<0.05)；觀察組的總併髮癥髮生率為10.0%，明顯低于對照組的15.0%，差異有統計學意義(P<0.05)。結論食管癌術前行半量放療，可改善患者的生活質量，延長生存期，減少轉移和複髮，延長遠期生存率，對保障患者預後有非常重要的意義。
목적：탐토식관암술전반량방료적림상효과。방법선취본원종류과2012년4월~2013년4월수치적80례식관암환자작위연구대상，기중가채취직접수술적40례설위대조조，40례수술전반량방료재행수술적설위관찰조。비교량조적림상총절제술솔、근제술절제솔、구역림파결전이솔、단단잔암양성솔급수방1년생존솔，관찰상관병발증발생적정황。결과관찰조적림상총절제술솔、근제술절제솔화수방1년생존솔명현고우대조조，구역림파결전이솔화단단잔암양성솔명현저우대조조，차이유통계학의의(P<0.05)；관찰조적총병발증발생솔위10.0%，명현저우대조조적15.0%，차이유통계학의의(P<0.05)。결론식관암술전행반량방료，가개선환자적생활질량，연장생존기，감소전이화복발，연장원기생존솔，대보장환자예후유비상중요적의의。
Objective To explore the application of half-dose radiotherapy in the pre-operation of esophagus cancer. Methods 80 patients with esophagus cancer treated admitted into Department of Oncology in our hospital from April 2012 to April 2013 were selected,of whom,40 cases taken with direct operation for treatment were as control group,40 cases taken with half-dose radiotherapy in the pre-operation were as observation group.The total clinical resection rate, eradicate resection rate,regional lymph node metastasis rate,residual stump positive rate of cancer,follow-up for 1-year survival rate between the two groups was compared,related complications were recorded. Results The total clinical re-section rate,eradicate resection rate,follow-up for 1-year survival rate in observation group was higher than that in con-trol group,regional lymph node metastasis rate and residual stump positive rate of cancer was lower than that in control group,the difference was significant (P<0.05).The incidence of complication in observation group was 10.0%,lower than 15.0% in control group,the difference was significant (P<0.05). Conclusion Half-dose radiotherapy in the pre-opera-tion of esophagus cancer can improve living quality,prolong lifetime,reduce metastasis and recurrence,and lengthen long-term survival rate,which all have important significances in guaranteeing patient’s prognosis.
