CAJ | 학술논문

目的：探究血浆和肽素、NT－proBNP 浓度对慢性心力衰竭患者生存状况的评估效果。方法：选取2007年5月至2013年5月确诊并住院的慢性心力衰竭患者150例，根据患者的血浆和肽素及NT－proBNP浓度分为高浓度组和低浓度组，比较两组患者的心脏功能指标。比较不同心功能分级患者的NT－proBNP浓度。出院后随访一年，根据随访结果分为无复发组和心脏事件组，比较两组患者的血浆和肽素及NT－proBNP浓度。结果：低浓度组患者LVEF、LVESD、LVEDD等指标均优于高浓度组。心力衰竭患者的心功能分级越差， NT－proBNP 浓度越高。心脏事件组的血浆和肽素及NT－proBNP浓度均高于无复发组。以上差异均具有统计学意义（ P＜0．05）。结论：血浆和肽素、NT－proB－NP浓度对慢性心力衰竭患者生存状况的评估效果良好。慢性心衰患者的血浆和肽素及NT－proBNP浓度越高，心脏功能指标越差，发生心脏事件的概率越大，即生存状况越差。
목적：탐구혈장화태소、NT－proBNP 농도대만성심력쇠갈환자생존상황적평고효과。방법：선취2007년5월지2013년5월학진병주원적만성심력쇠갈환자150례，근거환자적혈장화태소급NT－proBNP농도분위고농도조화저농도조，비교량조환자적심장공능지표。비교불동심공능분급환자적NT－proBNP농도。출원후수방일년，근거수방결과분위무복발조화심장사건조，비교량조환자적혈장화태소급NT－proBNP농도。결과：저농도조환자LVEF、LVESD、LVEDD등지표균우우고농도조。심력쇠갈환자적심공능분급월차， NT－proBNP 농도월고。심장사건조적혈장화태소급NT－proBNP농도균고우무복발조。이상차이균구유통계학의의（ P＜0．05）。결론：혈장화태소、NT－proB－NP농도대만성심력쇠갈환자생존상황적평고효과량호。만성심쇠환자적혈장화태소급NT－proBNP농도월고，심장공능지표월차，발생심장사건적개솔월대，즉생존상황월차。
Objective:To explore the evaluation effect of plasma copeptin, NT-proBNP concentration on the survival status of patients with chronic heart failure ( CHF) .Method:150 cases of patients with CHF were selected who diagnosed and hospitalized in our hospital from May 2007 to May 2013, according to the plasma and peptide hormone and NT-proBNP concentration, patients were divided into high concentration group and low concentration group , compared cardiac function index of two groups patients and NT-proBNP concentration of patients with different functional grading.Following up for one year after discharging, ac-cording to the result, patients were divided into non recurrence group and heart event group, compared plas-ma and peptide hormone and NT-proBNP concentration of two groups patients.Result: LVEF, LVESD, LVEDD and other indicators of the patients of low concentration group were better than the high concentration group.The worse classification of cardiac function in patients with heart failure,the higher concentration of NT-proBN plasma and peptide and NT-proBNP concentrations of heart event group were higher in recur-rence-free group.The above differences had statistical significance ( P <0.05) .Conclusion:The evaluation effect of plasma copeptin, NT-proBNP concentration on the survival status of patients with CHF is good.The higher plasma and peptide in and NT-proBNP concentration of patients with chronic heart failure is , the worse index of the heart function,and the greater the probability of occurrence of cardiac events, namely the worse survival situation .